Phys Vivas · haematological
Iron Deficiency — Viva Defence
Structured DCE viva for iron deficiency: long-case defence of a postmenopausal woman with iron-deficiency anaemia — malignancy workup, iron replacement strategy, and the ferritin-in-inflammation and treatment-failure probes.
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Opening statement (SASPOP, delivered aloud)
"Mrs Ward is a 61-year-old postmenopausal woman with confirmed, clinically significant iron-deficiency anaemia — Hb 82 with a ferritin of 11. Her main problems are: first, the anaemia itself and its symptoms; second, that iron deficiency in a postmenopausal woman is occult gastrointestinal blood loss until proven otherwise, so this is a potential malignancy presentation; and third, she needs iron replacement with a monitored response. I would like to assess her for GI and gynaecological sources, arrange bidirectional endoscopy and coeliac serology, and replete her iron with a defined follow-up plan." [1] [3]
References7ShowHide
- [1]Snook J, Bhala N, Beales ILP, et al. British Society of Gastroenterology guidelines for the management of iron deficiency anaemia in adults Gut, 2021.PMID 34497146
- [2]Rockey DC, Cello JP. Evaluation of the gastrointestinal tract in patients with iron-deficiency anemia N Engl J Med, 1993.PMID 8179652
- [3]Camaschella C. Iron-deficiency anemia N Engl J Med, 2015.PMID 25946282
- [4]Ludvigsson JF, Bai JC, Biagi F, et al. Diagnosis and management of adult coeliac disease: guidelines from the British Society of Gastroenterology Gut, 2014.PMID 24917550
- [5]Stoffel NU, Cercamondi CI, Brittenham G, et al. Iron absorption from oral iron supplements given on consecutive versus alternate days and as single morning doses versus twice-daily split dosing in iron-depleted women: two open-label, randomised controlled trials Lancet Haematol, 2017.PMID 29032957
- [6]Hershko C, Camaschella C. How I treat unexplained refractory iron deficiency anemia Blood, 2014.PMID 24215034
- [7]Schaefer B, Tobiasch M, Viveiros A, et al. Hypophosphataemia after treatment of iron deficiency with intravenous ferric carboxymaltose or iron isomaltoside-a systematic review and meta-analysis Br J Clin Pharmacol, 2021.PMID 33188534