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Phys Topicsgeneral-medicine

Phys · general-medicine

Neurological Examination — Speech and Higher Mental Function

Also known as speech examination · higher mental function · higher cortical function · cognitive assessment · aphasia examination · dysphasia · dysarthria · dysphonia · Broca aphasia · Wernicke aphasia · conduction aphasia · global aphasia · MMSE · MoCA · ACE-III · clock drawing test · mini-mental state examination · Montreal Cognitive Assessment

Classic DCE short-case routine for speech and higher mental function: the systematic six-step speech sequence, the aphasia classification (fluency, comprehension, repetition), dysarthria and dysphonia, the cognitive domains and their bedside tests (orientation, attention, memory, language, visuospatial, executive), the MMSE, MoCA and ACE-III, a say-aloud presentation template, examiner discussion and the pitfalls that fail candidates — for FRACP DCE, MRCP PACES and ABIM preparation.

high5 referencesUpdated 26 July 202616 min readVerification in progress

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Red flags

  • Acute onset of fluent, copious, meaningless speech with poor comprehension is Wernicke aphasia from a dominant-hemisphere superior temporal infarct — investigate and manage as an acute stroke within the thrombolysis window
  • A patient who suddenly stops speaking or produces only effortful, sparse, telegraphic fragments may have an acute Broca aphasia from an inferior frontal lobe stroke — examine for right hemiparesis and activate the stroke pathway
  • A fluent aphasia with preserved repetition that evolves over weeks to months, or a progressive anomia, is primary progressive aphasia — a neurodegenerative syndrome, not a stroke, and needs urgent neurology and MRI
  • An acute confusional state can mimic a Wernicke aphasia — the speech is incoherent and comprehension appears poor, but the disordered thinking, fluctuating attention and altered consciousness point to delirium, not a focal language lesion
  • Acute dysarthria with facial and limb weakness is brainstem or hemisphere stroke until proven otherwise — dysarthria is a recognised stroke warning sign and warrants urgent imaging, never attribution to intoxication or fatigue alone
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Target exams

FRACP DCEMRCP PACESMRCP Part 1MRCP Part 2ABIM Internal Medicine

Red flags

  • Acute onset of fluent, copious, meaningless speech with poor comprehension is Wernicke aphasia from a dominant-hemisphere superior temporal infarct — investigate and manage as an acute stroke within the thrombolysis window
  • A patient who suddenly stops speaking or produces only effortful, sparse, telegraphic fragments may have an acute Broca aphasia from an inferior frontal lobe stroke — examine for right hemiparesis and activate the stroke pathway
  • A fluent aphasia with preserved repetition that evolves over weeks to months, or a progressive anomia, is primary progressive aphasia — a neurodegenerative syndrome, not a stroke, and needs urgent neurology and MRI
  • An acute confusional state can mimic a Wernicke aphasia — the speech is incoherent and comprehension appears poor, but the disordered thinking, fluctuating attention and altered consciousness point to delirium, not a focal language lesion
  • Acute dysarthria with facial and limb weakness is brainstem or hemisphere stroke until proven otherwise — dysarthria is a recognised stroke warning sign and warrants urgent imaging, never attribution to intoxication or fatigue alone
The one-line answer

Examine speech first, then cognition — because you cannot test comprehension or memory through a language the patient cannot use. Split the speech at the bedside with the aphasia-versus-dysarthria fork (writing is the decisive discriminator: the aphasic writes garbled, the dysarthric writes perfectly), classify any aphasia on three axes — fluency, comprehension, repetition — and only then map the six cognitive domains: orientation, attention, memory, language, visuospatial, executive. Aphasia localises to the dominant-hemisphere language network; dysarthria localises anywhere along the motor pathway from cortex to muscle.[1]

Meet the patient

Mrs Kaur, seventy-two, is two hours into a sudden torrent of fluent, confident speech that carries no meaning — word after word, grammatically formed, signifying nothing. She seems unaware anything is wrong. She manages "close your eyes" but not "point to the door, then the window," and she cannot repeat "no ifs, ands, or buts." The ward registrar calls it delirium.[1]

This is the short case that rewards structure, not signs. The two questions that decide Mrs Kaur's next hour decide every speech-and-cognition station: is this a language disorder (aphasia) or a motor speech disorder (dysarthria)? and if it is aphasia, where in the dominant hemisphere does the lesion sit? A fluent, empty, paraphasic speaker with poor comprehension and anosognosia is Wernicke aphasia from a dominant superior-temporal infarct until proven otherwise — and the stroke pathway is activated before any cognitive score is recorded.[1]

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References5ShowHide
  1. [1]Folstein MF, Folstein SE, McHugh PR Mini-mental state. A practical method for grading the cognitive state of patients for the clinician J Psychiatr Res, 1975.PMID 1202204
  2. [2]Nasreddine ZS, Phillips NA, Bédirian V, et al. The Montreal Cognitive Assessment, MoCA: a brief screening tool for mild cognitive impairment J Am Geriatr Soc, 2005.PMID 15817019
  3. [3]Hsieh S, Schubert S, Hoon C, Mioshi E, Hodges JR Validation of the Addenbrooke's Cognitive Examination III in frontotemporal dementia and Alzheimer's disease Dement Geriatr Cogn Disord, 2013.PMID 23949210
  4. [4]Brady MC, Kelly H, Godwin J, Enderby P, Campbell P Speech and language therapy for aphasia following stroke Cochrane Database Syst Rev, 2016.PMID 27245310
  5. [5]Park J, Jeong E, Seomun G The clock drawing test: A systematic review and meta-analysis of diagnostic accuracy J Adv Nurs, 2018.PMID 30047147

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