Phys Written Answers · pharmacological
Therapeutic Drug Monitoring — Written Clinical Reasoning
DCE-style written reasoning for Therapeutic Drug Monitoring.
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Target exams
SAQ 1 — Integrated plan (12 marks)
Prompt: Provide a prioritised problem list and management sequence for this presentation. [1] [2]
Model Answer
1. Frame and red flags (3 marks) [1]
State the working diagnosis/syndrome, acuity, and what would force emergency treatment now. [1] [2]
2. Discriminating assessment (3 marks) [2]
List the key history, examination and investigations that separate dangerous differentials from benign mimics. [1] [2]
3. Treatment sequence (4 marks) [1] [3]
Immediate stabilisation, disease-specific therapy, monitoring, and complications prevention. [1] [2] [3]
4. Follow-up and communication (2 marks) [2]
Disposition, safety-net advice, and who owns follow-up. [1] [2]
References3ShowHide
- [1]Kang JS, Lee MH Overview of therapeutic drug monitoring. Korean J Intern Med, 2009.PMID 19270474
- [2]Rybak MJ, Le J, Lodise TP, Levine DP, et al. Therapeutic Monitoring of Vancomycin for Serious Methicillin-resistant Staphylococcus aureus Infections: A Revised Consensus Guideline and Review by the American Society of Health-system Pharmacists, the Infectious Diseases Society of America, the Pediatric Infectious Diseases Society, and the Society of Infectious Diseases Pharmacists. Clin Infect Dis, 2020.PMID 32658968
- [3]Krishnan N, Perazella MA Diagnosis and Management of Acute and Chronic Lithium-Associated Nephrotoxicity. J Am Soc Nephrol, 2026.PMID 42247265