Phys Clinical Cases · pharmacological
Toxic Alcohols — DCE Clinical Case
DCE long-case and short-case station for Toxic Alcohols.
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FRACP DCEMRCP PACES
Prompt
DCE long-case and short-case station for Toxic Alcohols.
Toxic Alcohols — Clinical Case
DCE Long Case
Patient brief
Patient: A middle-aged or older adult with multimorbidity and a presentation centred on Toxic Alcohols. [1]
Presenting complaint: Subacute or acute symptoms referable to Toxic Alcohols, with enough detail to force prioritisation. [1] [2]
Past history: Common cardiometabolic and organ comorbidities that interact with the plan. [2]
Medications: A polypharmacy list that includes at least one interaction or dosing issue. [2]
Examination: Key positives and critical negatives for dangerous differentials. [1]
Investigations: A small set of results that change management. [1] [2]
Tasks
- Present a prioritised problem list. [1]
- Defend investigations and immediate therapy. [1] [2]
- Provide safety-net and follow-up advice. [2]
Model discussion points
- Working diagnosis and acuity. [1]
- Differentials and discriminators. [2]
- Treatment sequence and monitoring. [1] [2] [3]
- Multimorbidity and communication. [2]
References3ShowHide
- [1]Brent J, McMartin K, Phillips S, Burkhart KK, et al. Fomepizole for the treatment of ethylene glycol poisoning. Methylpyrazole for Toxic Alcohols Study Group N Engl J Med, 1999.PMID 10080845
- [2]Brent J, McMartin K, Phillips S, et al. Fomepizole for the treatment of methanol poisoning N Engl J Med, 2001.PMID 11172179
- [3]Ghannoum M, Gosselin S, Hoffman RS, et al. Extracorporeal treatment for ethylene glycol poisoning: systematic review and recommendations from the EXTRIP workgroup Crit Care, 2023.PMID 36765419