Phys Clinical Cases · pharmacological
Salicylate Toxicity — DCE Clinical Case
DCE long-case and short-case station for Salicylate Toxicity.
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FRACP DCEMRCP PACES
Prompt
DCE long-case and short-case station for Salicylate Toxicity.
Salicylate Toxicity — Clinical Case
DCE Long Case
Patient brief
Patient: A middle-aged or older adult with multimorbidity and a presentation centred on Salicylate Toxicity. [1]
Presenting complaint: Subacute or acute symptoms referable to Salicylate Toxicity, with enough detail to force prioritisation. [1] [2]
Past history: Common cardiometabolic and organ comorbidities that interact with the plan. [2]
Medications: A polypharmacy list that includes at least one interaction or dosing issue. [2]
Examination: Key positives and critical negatives for dangerous differentials. [1]
Investigations: A small set of results that change management. [1] [2]
Tasks
- Present a prioritised problem list. [1]
- Defend investigations and immediate therapy. [1] [2]
- Provide safety-net and follow-up advice. [2]
Model discussion points
- Working diagnosis and acuity. [1]
- Differentials and discriminators. [2]
- Treatment sequence and monitoring. [1] [2] [3]
- Multimorbidity and communication. [2]
References3ShowHide
- [1]Juurlink DN, Gosselin S, Kielstein JT, et al. Extracorporeal Treatment for Salicylate Poisoning: Systematic Review and Recommendations From the EXTRIP Workgroup Ann Emerg Med, 2015.PMID 25986310
- [2]Proudfoot AT, Krenzelok EP, Vale JA Position Paper on urine alkalinization J Toxicol Clin Toxicol, 2004.PMID 15083932
- [3]Hoegberg LCG, Gosselin S, Buckley NA, Wood DM, et al. Recommendations from the Clinical Toxicology Recommendations Collaborative on the administration of activated charcoal in acute oral overdose Clin Toxicol (Phila), 2026.PMID 41906697