Phys Clinical Cases · general-medicine
Primary Immunodeficiency in Adults — DCE Clinical Case
DCE long-case clinical station: comprehensive assessment of a 22-year-old man presenting with his second episode of invasive meningococcal disease in 18 months, leading to the diagnosis of terminal complement (C6) deficiency — covering the CH50 and AH50 interpretation, the preventive plan (meningococcal vaccination, standby antibiotics, family screening), the distinction from properdin deficiency, and the long-term surveillance and counselling — structured for FRACP DCE and MRCP PACES.
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DCE long-case clinical station: comprehensive assessment of a 22-year-old man presenting with his second episode of invasive meningococcal disease in 18 months, leading to the diagnosis of terminal complement (C6) deficiency — covering the CH50 and AH50 interpretation, the preventive plan (meningococcal vaccination, standby antibiotics, family screening), the distinction from properdin deficiency, and the long-term surveillance and counselling — structured for FRACP DCE and MRCP PACES.
Primary Immunodeficiency in Adults — Clinical Case
References2ShowHide
- [1]Boyle JM, Buckley RH Population prevalence of diagnosed primary immunodeficiency diseases in the United States J Clin Immunol, 2007.PMID 17577648
- [2]Figueroa JE, Densen P Infectious diseases associated with complement deficiencies Clin Microbiol Rev, 1991.PMID 1889047