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Oesophageal Disorders — DCE Clinical Case
DCE long-case station: progressive dysphagia with weight loss — the discriminating history, the epigastric and general examination, staging logic and the presentation of a suspected oesophageal malignancy.
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Prompt
DCE long-case station: progressive dysphagia with weight loss — the discriminating history, the epigastric and general examination, staging logic and the presentation of a suspected oesophageal malignancy.
Focused history — what you must establish
- The discriminating dysphagia history: solids first or liquids from the start; progressive or intermittent; localisation; regurgitation character (acidic versus bland undigested food); odynophagia as a separate symptom; and the tempo over weeks to months [1].
- Alarm inventory: weight loss and its amount, appetite, haematemesis or melaena, anaemia symptoms, voice change, persistent cough or aspiration episodes [1].
- Risk profile: smoking and alcohol (squamous risk), reflux duration and severity with central obesity (adenocarcinoma risk via Barrett's), prior caustic ingestion, achalasia history, and any prior endoscopy [2].
- The host for what may come: cardiorespiratory comorbidity, performance status and nutrition — the variables that decide whether neoadjuvant therapy and oesophagectomy are even on the table [3].
- The patient's frame: what he thinks is happening, what he fears, and who supports him — a five-month delay in presentation usually has a reason.
References5ShowHide
- [1]Liu LWC, Andrews CN, Armstrong D, et al. Clinical Practice Guidelines for the Assessment of Uninvestigated Esophageal Dysphagia J Can Assoc Gastroenterol, 2018.PMID 31294391
- [2]Katz PO, Dunbar KB, Schnoll-Sussman FH, et al. ACG Clinical Guideline for the Diagnosis and Management of Gastroesophageal Reflux Disease Am J Gastroenterol, 2022.PMID 34807007
- [3]van Hagen P, Hulshof MC, van Lanschot JJ, et al. Preoperative chemoradiotherapy for esophageal or junctional cancer N Engl J Med, 2012.PMID 22646630
- [4]Shapiro J, van Lanschot JJB, Hulshof MCCM, et al. Neoadjuvant chemoradiotherapy plus surgery versus surgery alone for oesophageal or junctional cancer (CROSS): long-term results of a randomised controlled trial Lancet Oncol, 2015.PMID 26254683
- [5]Vaezi MF, Pandolfino JE, Yadlapati RH, et al. ACG Clinical Guidelines: Diagnosis and Management of Achalasia Am J Gastroenterol, 2020.PMID 32773454