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Phys Clinical Casesendocrine

Phys Clinical Cases · endocrine

Multiple Endocrine Neoplasia — DCE Clinical Case

DCE long-case and short-case station for Multiple Endocrine Neoplasia.

1 min readVerification in progress

Target exams

FRACP DCEMRCP PACES
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Study tools

Target exams

FRACP DCEMRCP PACES
Prompt
DCE long-case and short-case station for Multiple Endocrine Neoplasia.

Multiple Endocrine Neoplasia — Clinical Case

DCE Long Case

Patient brief

Patient: A middle-aged or older adult with multimorbidity and a presentation centred on Multiple Endocrine Neoplasia. [1]

Presenting complaint: Subacute or acute symptoms referable to Multiple Endocrine Neoplasia, with enough detail to force prioritisation. [1] [2]

Past history: Common cardiometabolic and organ comorbidities that interact with the plan. [2]

Medications: A polypharmacy list that includes at least one interaction or dosing issue. [2]

Examination: Key positives and critical negatives for dangerous differentials. [1]

Investigations: A small set of results that change management. [1] [2]

Tasks

  1. Present a prioritised problem list. [1]
  2. Defend investigations and immediate therapy. [1] [2]
  3. Provide safety-net and follow-up advice. [2]

Model discussion points

  • Working diagnosis and acuity. [1]
  • Differentials and discriminators. [2]
  • Treatment sequence and monitoring. [1] [2] [3]
  • Multimorbidity and communication. [2]
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References6ShowHide
  1. [1]Thelen AE, Hogan EM, Su MW, McHenry CR The Genetics of Familial Neoplastic Thyroid Disease and Primary Hyperparathyroidism Surg Clin North Am, 2026.PMID 42419309
  2. [2]Noso S, Miki H, Hiromine Y, Babaya N, et al. Metachronous multiple insulinomas in oculo-facio-cardio-dental syndrome harboring a novel BCOR deletion: a case report with review of literature Endocr J, 2026.PMID 42324136
  3. [3]Nosé V, Canberk S, Baloch Z Recognizing Familial Thyroid Neoplasia: The Pathologist's Role in Diagnosis and Management Adv Anat Pathol, 2026.PMID 42319956
  4. [4]Pawlak KM, Jagielski M, Papanikolaou IS, Hong W, et al. Pancreatic cystic lesions in hereditary syndromes: Diagnostic role of endoscopic ultrasound Best Pract Res Clin Gastroenterol, 2026.PMID 42167859
  5. [5]Mariën L, Chhajlani S, De Herdt C, Ceulemans K, et al. Germline MEN1 testing patterns in patients with neuroendocrine tumors: A 12-year retrospective analysis within NETwerk, an ENETS center of excellence J Neuroendocrinol, 2026.PMID 42140697
  6. [6]Moura MJ, Chatterjee A, Wali S, Garza DR, et al. Refractory immune-related adverse events (irAEs) associated with immune checkpoint inhibitor therapy: a multiorgan management review Expert Opin Drug Saf, 2026.PMID 41995025
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