Phys Clinical Cases · general-medicine
Clinical Research AND Research Ethics — DCE Clinical Case
DCE long-case and short-case station for Clinical Research AND Research Ethics.
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FRACP DCEMRCP PACES
Prompt
DCE long-case and short-case station for Clinical Research AND Research Ethics.
Clinical Research AND Research Ethics — Clinical Case
DCE Long Case
Patient brief
Patient: A middle-aged or older adult with multimorbidity and a presentation centred on Clinical Research AND Research Ethics. [1]
Presenting complaint: Subacute or acute symptoms referable to Clinical Research AND Research Ethics, with enough detail to force prioritisation. [1] [2]
Past history: Common cardiometabolic and organ comorbidities that interact with the plan. [2]
Medications: A polypharmacy list that includes at least one interaction or dosing issue. [2]
Examination: Key positives and critical negatives for dangerous differentials. [1]
Investigations: A small set of results that change management. [1] [2]
Tasks
- Present a prioritised problem list. [1]
- Defend investigations and immediate therapy. [1] [2]
- Provide safety-net and follow-up advice. [2]
Model discussion points
- Working diagnosis and acuity. [1]
- Differentials and discriminators. [2]
- Treatment sequence and monitoring. [1] [2] [3]
- Multimorbidity and communication. [2]
References8ShowHide
- [1]Vincens N, Persson Waye K, Smith MG, Lercher P, et al. Sleep as a potential link between exposome, mental health and cognitive development in children and adolescents - a scoping review Arch Public Health, 2026.PMID 42469926
- [2]Huang F, Chen H, Mei S, Xue H, et al. Single-cell transcriptome analysis in ovarian steroid cell tumors-not otherwise specified J Ovarian Res, 2026.PMID 42469914
- [3]Seyedi SZ, Abedi A, Mollashahi B, Namazinia M, et al. Late presentation of an anomalous left coronary artery originating from the pulmonary artery (ALCAPA) in a 70-year-old male: a case report J Med Case Rep, 2026.PMID 42469911
- [4]Ugovšek S, Zemljič G, Cerar A, Frljak S, et al. Case report: decommissioning of a left ventricular assist device following reverse remodeling in non-ischemic cardiomyopathy patient J Cardiothorac Surg, 2026.PMID 42469851
- [5]Dannenberg VC, Amin R, Anagnostopoulos G, Adeleye A, et al. Establishing polysomnographic criteria for initiation of non-invasive ventilation in children with neuromuscular diseases J Clin Sleep Med, 2026.PMID 42469579
- [6]Deressa JD, Behaksra SW, Molla E, Letebo A, et al. Therapeutic efficacy of artemether-lumefantrine plus single low dose primaquine for the treatment of uncomplicated Plasmodium falciparum malaria in a high transmission setting, Western Ethiopia PLoS One, 2026.PMID 42467750
- [7]Xi Y, Yao T, Zhang C, Zhuang T Effectiveness of safety care and clinical nursing pathway in patients undergoing cardiovascular intervention: a randomized controlled trial Perioper Med (Lond), 2026.PMID 42469924
- [8]Marks FJ, Walters SJ, Sutton L, Jacques RM What statistical methods are more appropriate for predicting recruitment at the design stage of a randomised controlled trial? Trials, 2026.PMID 42469922