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Phys Clinical Casespharmacological

Phys Clinical Cases · pharmacological

Cardiac Glycoside — DCE Clinical Case

DCE long-case and short-case station for Cardiac Glycoside.

1 min readVerification in progress

Target exams

FRACP DCEMRCP PACES
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Study tools

Target exams

FRACP DCEMRCP PACES
Prompt
DCE long-case and short-case station for Cardiac Glycoside.

Cardiac Glycoside — Clinical Case

DCE Long Case

Patient brief

Patient: A middle-aged or older adult with multimorbidity and a presentation centred on Cardiac Glycoside. [1]

Presenting complaint: Subacute or acute symptoms referable to Cardiac Glycoside, with enough detail to force prioritisation. [1] [2]

Past history: Common cardiometabolic and organ comorbidities that interact with the plan. [2]

Medications: A polypharmacy list that includes at least one interaction or dosing issue. [2]

Examination: Key positives and critical negatives for dangerous differentials. [1]

Investigations: A small set of results that change management. [1] [2]

Tasks

  1. Present a prioritised problem list. [1]
  2. Defend investigations and immediate therapy. [1] [2]
  3. Provide safety-net and follow-up advice. [2]

Model discussion points

  • Working diagnosis and acuity. [1]
  • Differentials and discriminators. [2]
  • Treatment sequence and monitoring. [1] [2] [3]
  • Multimorbidity and communication. [2]
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References6ShowHide
  1. [1]Kumar A, Ul Haque Z, Rai A Evaluation of the Therapeutic Potential and Safety of Terminalia arjuna in Heart Failure Management: A Systematic Review and Meta-analysis of Randomized Controlled Trials Ann Afr Med, 2026.PMID 42389976
  2. [2]Ecker PAM, Schaper A, Bräunig HJ, Seifert R Critical analysis of digitalis glycosides: declining use but increasing poison-center exposure cases for digitoxin Eur J Clin Pharmacol, 2026.PMID 42334625
  3. [3]Kotecha D, Bunting KV, Gill SK, et al. Effect of Digoxin vs Bisoprolol for Heart Rate Control in Atrial Fibrillation on Patient-Reported Quality of Life: The RATE-AF Randomized Clinical Trial JAMA, 2020.PMID 33351042
  4. [4]Mehra MR, Vukicevic M, Desai AS Digitalis Today: From Doctrine to Disrepute to Disciplined Reconsideration J Card Fail, 2026.PMID 42331138
  5. [5]Bavendiek U, Bauersachs J [Digitalis and Heart Failure] Dtsch Med Wochenschr, 2026.PMID 42214363
  6. [6]Jerical C, Ahmed E, Asifa S, Ariba S, et al. Therapeutic Impact of Cardiac Glycosides (Digoxin and Digitoxin) in Heart Failure With Reduced Ejection Fraction: A Systematic Review Cardiol Rev, 2026.PMID 42132739
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