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Paeds Vivasneurology-neurodisability-and-neuromuscular

Paeds Vivas · neurology-neurodisability-and-neuromuscular

Spinal cord compression and transverse myelitis — branching viva

Branching viva on the acute spinal cord syndrome in childhood: recognising that new back pain plus a neurological deficit is a cord emergency until an emergency whole-spine MRI proves otherwise, separating the structural compressive lesion (malignancy, epidural abscess) that needs dexamethasone and surgical decompression within twenty-four to forty-eight hours from the intrinsic inflammatory transverse myelitis that needs high-dose methylprednisolone, the Transverse Myelitis Consortium 2002 criteria, the longitudinally extensive lesion pointing to neuromyelitis optica spectrum disorder or MOG-antibody-associated disease, and the principle that ambulation at presentation is the strongest predictor of outcome.

branching clinical structured oral3 min readVerification in progress

Target exams

RACP DCEMRCPCH ClinicalRCPSC Pediatrics
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Target exams

RACP DCEMRCPCH ClinicalRCPSC Pediatrics
Prompt
Emergency department: a nine-year-old with three days of nocturnal thoracic back pain, a weak left leg, and acute urinary retention, with a T10 sensory level on examination. The examiner asks: what is the single most important next investigation, what is the fork it resolves, and what determines the urgency - then branches to a febrile immunocompromised teenager with an epidural collection, to a twelve-year-old with a six-segment intrinsic lesion and a viral prodrome, and finally to a four-year-old who simply refuses to walk.

Opening branch — the nine-year-old with nocturnal back pain and a weak leg

A previously well nine-year-old presents with three days of thoracic back pain that wakes him at night and is worse lying flat, then a weak left leg and acute urinary retention, with a T10 sensory level. The candidate must first state that the single most important next investigation is an emergency whole-spine MRI with gadolinium, performed within hours and never delayed for bloods or a lumbar puncture. The teaching point is that the MRI - not the history and not the bloods - resolves the fork between a compressive structural lesion, a surgical emergency needing dexamethasone and decompression, and an inflammatory transverse myelitis, a medical emergency needing methylprednisolone. [1] [4]

The examiner probes the symptom sequence and the urgency. The candidate describes the classic order of a compressive lesion - back pain, then radicular pain, then motor weakness, then a sensory level, then sphincter loss - and notes that nocturnal back pain worse lying flat, with a sensory level and urinary retention, is an established lesion with a narrow salvage window. The candidate states that ambulation at presentation is the single strongest predictor of outcome, and that the surgical decompression is timed within twenty-four to forty-eight hours of the loss of ambulation because the cord converts from a reversible oedematous phase to irreversible infarction within that window. [4]

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References5ShowHide
  1. [1]Transverse Myelitis Consortium Working Group. Proposed diagnostic criteria and nosology of acute transverse myelitis. Neurology, 2002.PMID 12236201
  2. [2]Pidcock FS, Krishnan C, Crawford TO, Salorio CF, Trovato M, Kerr DA, et al. Acute transverse myelitis in childhood: center-based analysis of 47 cases. Neurology, 2007.PMID 17470749
  3. [3]Wingerchuk DM, Banwell B, Bennett JL, Cabre P, Carroll W, Chitnis T, et al. International consensus diagnostic criteria for neuromyelitis optica spectrum disorders. Neurology, 2015.PMID 26092914
  4. [4]Prasad D, Schiff D. Malignant spinal-cord compression. Lancet Oncol, 2005.PMID 15629272
  5. [5]Darouiche RO. Spinal epidural abscess. N Engl J Med, 2006.PMID 17093252
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