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Paeds Vivasfetal-neonatal-and-perinatal

Paeds Vivas · fetal-neonatal-and-perinatal

Preterm infant — viva

Branching viva on preterm infant stabilisation, respiratory management, nutrition, complications and longitudinal follow-up.

branching clinical structured oral2 min readVerification in progress

Target exams

RACP DCEMRCPCH ClinicalRCPSC Pediatrics
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Target exams

RACP DCEMRCPCH ClinicalRCPSC Pediatrics
Prompt
Delivery room: a 28-week preterm infant is born after spontaneous preterm labour with grunting and oxygen need.

Stem

Examiner-led viva on the preterm infant from delivery-room stabilisation through longitudinal follow-up. [6]

Examiner: The infant is grunting and desaturating. How do you open in the delivery room? [6]

Strong answer: I dry and warm the infant under a radiant heater with a polyethylene wrap, assess tone, breathing and heart rate, and provide gentle CPAP at 5–7 cm water for the grunting baby. I start with air or low oxygen — 21 to 30 per cent — and titrate upward against a pre-ductal saturation nomogram, avoiding routine 100 per cent oxygen. [6]

Examiner: What about the cord? [5]

Strong answer: If the infant does not need immediate resuscitation, I defer cord clamping for 30 to 60 seconds. The Seidler individual-participant-data network meta-analysis shows deferred clamping reduces mortality compared with immediate clamping in preterm infants. [5]

Examiner: The oxygen need rises to 35 per cent on CPAP. What now? [7]

Strong answer: This is established respiratory distress syndrome. I give rescue surfactant and extubate back to CPAP as quickly as possible. The SUPPORT trial established that early CPAP with selective surfactant is viable in extremely preterm infants and reduces intubation without worsening outcomes. [7]

Examiner: When do you start caffeine and why? [8]

Strong answer: I start caffeine citrate early in ventilated or CPAP-dependent very preterm infants for apnoea prevention and extubation readiness. The CAP trial showed caffeine improves survival without neurodevelopmental disability at 18 to 21 months, with benefits persisting to age five — so it is both symptomatic and neuroprotective. [8] [9]

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References9ShowHide
  1. [5]Seidler AL Short, medium, and long deferral of umbilical cord clamping compared with umbilical cord milking and immediate clamping at preterm birth: a systematic review and network meta-analysis with individual participant data. Lancet, 2023.PMID 37977170
  2. [6]Sweet DG European Consensus Guidelines on the Management of Respiratory Distress Syndrome: 2022 Update. Neonatology, 2023.PMID 36863329
  3. [7]Finer NN, Carlo WA, Walsh MC, et al. Early CPAP versus surfactant in extremely preterm infants. N Engl J Med, 2010.PMID 20472939
  4. [8]Schmidt B Caffeine therapy for apnea of prematurity. N Engl J Med, 2006.PMID 16707748
  5. [9]Schmidt B Survival without disability to age 5 years after neonatal caffeine therapy for apnea of prematurity. JAMA, 2012.PMID 22253394
  6. [11]Stoll BJ Trends in Care Practices, Morbidity, and Mortality of Extremely Preterm Neonates, 1993-2012. JAMA, 2015.PMID 26348753
  7. [12]Fierson WM Screening Examination of Premature Infants for Retinopathy of Prematurity. Pediatrics, 2018.PMID 30478242
  8. [14]Quigley M Formula versus donor breast milk for feeding preterm or low birth weight infants. Cochrane Database Syst Rev, 2019.PMID 31322731
  9. [20]Moore T Neurological and developmental outcome in extremely preterm children born in England in 1995 and 2006: the EPICure studies. BMJ, 2012.PMID 23212880
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