Paeds Vivas · fetal-neonatal-and-perinatal
Parenteral nutrition in neonates — viva
Branching viva.
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The examiner hands you the prescription chart for a 780 g infant born at 26 weeks, now two hours old, with a umbilical venous catheter in place. The team asks you to start parenteral nutrition. [3]
Examiner: What is your opening approach to prescribing PN for this infant? [3]
Strong answer: I would frame PN as a bridge, not a destination, and begin early aggressive nutrition to prevent the catabolic crisis of extreme prematurity. Within the first hours of life I would start amino acids at 1.5 to 2 g/kg/day, a glucose infusion rate of 4 to 6 mg/kg/min, and lipid at 1 to 2 g/kg/day, then advance to the ESPGHAN targets over the first days. I would secure central access, protect the line with a dedicated lumen and a no-break policy, and set up the daily monitoring of glucose, weight, electrolytes, triglycerides and liver function. [4] [3]
You have read the opening of this viva. The complete unit — every section and its primary-source references — is part of the Paediatrics Fellowship fellowship atlas.
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- [1]Koletzko B Guidelines on Paediatric Parenteral Nutrition of the European Society of Paediatric Gastroenterology, Hepatology and Nutrition (ESPGHAN) and the European Society for Clinical Nutrition and Metabolism (ESPEN), supported by the European Society of Paediatric Research (ESPR). Journal of Pediatric Gastroenterology and Nutrition, 2005.PMID 16254497
- [2]Fivez T Early versus Late Parenteral Nutrition in Critically Ill Children. New England Journal of Medicine, 2016.PMID 26975590
- [3]te Braake FW Amino acid administration to premature infants directly after birth. Journal of Pediatrics, 2005.PMID 16227030
- [4]van Goudoever JB ESPGHAN/ESPEN/ESPR/CSPEN guidelines on pediatric parenteral nutrition: Amino acids. Clinical Nutrition, 2018.PMID 30100107
- [5]Hojsak I ESPGHAN position paper: intravenous lipid emulsions and risk of hepatotoxicity. Journal of Pediatric Gastroenterology and Nutrition, 2016.PMID 26825766
- [6]Puder M Parenteral fish oil improves outcomes in patients with parenteral nutrition-associated liver injury. Annals of Surgery, 2009.PMID 19661785