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Paeds Vivaspaediatric-dermatology

Paeds Vivas · paediatric-dermatology

Nappy dermatitis — branching viva

Branching viva on nappy dermatitis: separating the irritant from the candidal subtype at the bedside by the fold involvement and the satellite lesions, applying the stepwise management of the general skin care and the barrier and the antifungal, using the hydrocortisone 1 percent sparingly, and branching to the persistent rash and the broader differential of seborrhoeic, atopic, allergic, psoriatic, and zinc deficiency, and the Langerhans cell histiocytosis.

branching clinical structured oral3 min readVerification in progress

Target exams

RACP DCEMRCPCH ClinicalRCPSC Pediatrics
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Target exams

RACP DCEMRCPCH ClinicalRCPSC Pediatrics
Prompt
A nine-month-old boy is brought with a five-day nappy rash that spread into the groin folds after a course of amoxicillin for an ear infection. There are small red papules at the edge of the rash. The examiner asks: what is your diagnosis, how do you tell the irritant from the candidal subtype, what is the management — then branches to the pathophysiology of the barrier disruption and the Candida overgrowth, the dosing of the antifungal, the use of the hydrocortisone, the red flag of the persistent rash at seven days, and the broader differential including the zinc deficiency.

Branching framework

Open with the one-sentence problem representation. This is a candidal nappy dermatitis in a nine-month-old boy, precipitated by the recent amoxicillin course, superimposed on an irritant base. The decisive features are the involvement of the inguinal folds — which the irritant subtype spares — and the satellite papules at the edge, which are the pathognomonic feature of the candidal subtype. State the recognition aloud — the folds involved, the satellites present, the recent antibiotic course — before you discuss the management. The examiner is listening for whether you separate the subtypes at the bedside before you reach for the treatment. [1] [3]

Name the bedside distinction and the pathophysiology. The irritant subtype spares the folds because they are the skin least exposed to the urine and the faeces, and the candidal subtype involves them because the warm, moist, occluded fold is the environment where Candida thrives. The pathophysiology of the irritant subtype is the disruption of the stratum corneum by the moisture, the faecal enzymes, and the elevated pH under the occluded nappy, and the candidal subtype is the opportunistic overgrowth of Candida albicans on the disrupted skin. Be ready for the probe on the ammonia: the urease-producing organisms convert the urea to ammonia, raising the skin pH and activating the faecal proteases and lipases that digest the corneocyte barrier. [1] [3]

Branch to the management sequence. The management is the general skin care, the barrier preparation, and the antifungal. The nappy is changed every two to three hours and after every stool, the super-absorbent disposable nappy is used, the skin is cleansed with the warm water and the soft cloth — not the alcohol wipe — and the air exposure is encouraged. The zinc oxide paste at fifteen to forty percent or the petrolatum is applied generously at every change, and the old layer is gently wiped and not scrubbed off. The antifungal — the clotrimazole 1 percent or the miconazole 2 percent cream, twice daily for ten to fourteen days — is applied to the affected skin before the barrier layer. The hydrocortisone 1 percent, once or twice daily for three to five days, is added if the inflammation is intense, and the potent steroids are avoided because the occlusion increases the absorption and the atrophy risk. [5] [4]

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References7ShowHide
  1. [1]Chiriac A, Wollina U. Diaper dermatitis-a narrative review of clinical presentation, subtypes, and treatment Wien Med Wochenschr, 2024.PMID 37861874
  2. [2]Helms LE, Burrows HL. Diaper Dermatitis Pediatr Rev, 2021.PMID 33386307
  3. [3]Dutta A, Dutta M, Nag SS. Candidal Diaper Dermatitis Indian Pediatr, 2015.PMID 26713999
  4. [4]Taudorf EH, Jemec GBE, Hay RJ, et al. Cutaneous candidiasis - an evidence-based review of topical and systemic treatments to inform clinical practice J Eur Acad Dermatol Venereol, 2019.PMID 31287594
  5. [5]Blume-Peytavi U, Kanti V. Prevention and treatment of diaper dermatitis Pediatr Dermatol, 2018.PMID 29596731
  6. [6]Fölster-Holst R Differential diagnoses of diaper dermatitis Pediatr Dermatol, 2018.PMID 29596730
  7. [7]Prasad HR, Srivastava P, Verma KK. Diaper dermatitis--an overview Indian J Pediatr, 2003.PMID 14510084
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