Paeds Vivas · respiratory-sleep-and-airway
Laryngomalacia, tracheomalacia and vocal-cord dysfunction: Viva
Branching structured oral on dynamic airway collapse: localising the noisy airway by respiratory phase, the barking cough that does not respond to salbutamol, the spontaneously breathing bronchoscopy that diagnoses tracheomalacia, and the adolescent with exertional inspiratory stridor treated with breathing retraining.
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Target exams
Branch 1: Recognising the pattern that is not asthma
The candidate should immediately question the asthma label. A barking, seal-like cough with an expiratory wheeze that does not respond to a bronchodilator, and that may worsen after the reliever, is the classic picture of tracheomalacia rather than asthma. The history of repaired oesophageal atresia and tracheo-oesophageal fistula is the crucial clue, because these children have a structurally soft trachea from the shared foregut origin of the trachea and oesophagus. The recurrent chest infections fit a trachea that clears secretions poorly. [3]
The candidate should explain the localising principle: this is expiratory, intrathoracic noise, which points to the trachea, whereas asthma is small-airway disease that responds to bronchodilator. The mechanism of the salbutamol trap is that the drug relaxes airway smooth muscle and reduces the residual tone splinting the soft trachea open, so it can worsen the collapse. [1]
References4ShowHide
- [1]Carden KA, Boiselle PM, Waltz DA, et al. Tracheomalacia and tracheobronchomalacia in children and adults: an in-depth review. Chest, 2005.PMID 15764786
- [2]Wallis C, Alexopoulou E, Antón-Pacheco JL, et al. ERS statement on tracheomalacia and bronchomalacia in children. Eur Respir J, 2019.PMID 31320455
- [3]van der Zee DC, van Herwaarden MYA, Hulsker CCC, et al. Esophageal Atresia and Upper Airway Pathology. Clin Perinatol, 2017.PMID 29127957
- [4]Halvorsen T, Walsted ES, Bucca C, et al. Inducible laryngeal obstruction: an official joint European Respiratory Society and European Laryngological Society statement. Eur Respir J, 2017.PMID 28889105