Paeds Vivas · nephrology-urology-fluids-and-electrolytes
Hypokalaemia and hyperkalaemia — viva
Branching structured oral on hypokalaemia and hyperkalaemia in children, covering the three-axis classification, cardiac electrophysiology and ECG changes, the hyperkalaemia emergency ladder with calcium gluconate, salbutamol and insulin-dextrose, safe intravenous potassium replacement, hypomagnesaemia as a refractory cause, and the Bartter versus Gitelman distinction.
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"This is severe hyperkalaemia with cardiotoxic ECG changes — a widened QRS and peaked T waves — and it is a cardiac emergency. My first action is to give intravenous 10 percent calcium gluconate at 0.5 mL per kilogram, maximum about 10 mL, slowly over 5 minutes with continuous cardiac monitoring, to stabilise the myocardium. This does not lower the potassium, so I immediately follow with a shifting agent — nebulised salbutamol and insulin-dextrose — and I arrange definitive removal of potassium, likely dialysis given the acute kidney injury. I do not wait for a repeat potassium; the ECG tells me to act now." [2][3]
References6ShowHide
- [2]Rubens M; Kanaris C Fifteen-minute consultation: Emergency management of children presenting with hyperkalaemia. Arch Dis Child Educ Pract Ed, 2022.PMID 34344762
- [3]Masilamani K; van der Voort J The management of acute hyperkalaemia in neonates and children. Arch Dis Child, 2012.PMID 21920871
- [4]Viera AJ; Wouk N Potassium Disorders: Hypokalemia and Hyperkalemia. Am Fam Physician, 2015.PMID 26371733
- [5]Kemper MJ; Harps E; Hellwege HH; Müller-Wiefel DE Effective treatment of acute hyperkalaemia in childhood by short-term infusion of salbutamol. Eur J Pediatr, 1996.PMID 8789768
- [7]Moussavi K; Fitter S; Gabrielson SW; Koyfman A Management of Hyperkalemia With Insulin and Glucose: Pearls for the Emergency Clinician. J Emerg Med, 2019.PMID 31084947
- [8]Crnobrnja L; Metlapalli M; Jiang C; Govinna M The Association of Insulin-dextrose Treatment with Hypoglycemia in Patients with Hyperkalemia. Sci Rep, 2020.PMID 33328554