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Paeds Vivasfetal-neonatal-and-perinatal

Paeds Vivas · fetal-neonatal-and-perinatal

Fetal growth restriction and small-for-gestational-age infant — viva

Branching viva.

branching clinical structured oral2 min readVerification in progress

Target exams

RACP DCEMRCPCH Clinical
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Target exams

RACP DCEMRCPCH Clinical
Prompt
Bedside and antenatal-history interpretation station for a small-for-gestational-age infant.

Stem

The examiner hands you the antenatal summary of a 36-week infant: birthweight 2100 g (below the 3rd centile), maternal pre-eclampsia, absent end-diastolic flow on the umbilical artery Doppler, and a wasted neonate now in the nursery. [1]

Examiner: What is your opening approach to this infant? [1]

Strong answer: I would first classify this as fetal growth restriction rather than constitutional smallness, because the antenatal Doppler is abnormal and the infant is wasted. I would plot the weight, length and head circumference on a gestation- and sex-specific INTERGROWTH-21st chart, calculate the Ponderal Index, and judge symmetry. Then I would pre-empt the four neonatal complications — hypothermia, hypoglycaemia, polycythaemia and feeding difficulty — from the first feed, with warmth, early feeding, scheduled glucose monitoring and a selective haematocrit. [3] [7]

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References7ShowHide
  1. [1]Gordijn SJ Consensus definition of fetal growth restriction: a Delphi procedure. Ultrasound in Obstetrics & Gynecology, 2016.PMID 26909664
  2. [2]Figueras F Update on the diagnosis and classification of fetal growth restriction and proposal of a stage-based management protocol. Fetal Diagnosis and Therapy, 2014.PMID 24457811
  3. [3]Villar J International standards for newborn weight, length, and head circumference by gestational age and sex: the Newborn Cross-Sectional Study of the INTERGROWTH-21st Project. Lancet, 2014.PMID 25209487
  4. [4]Lees CC Perinatal morbidity and mortality in early-onset fetal growth restriction: cohort outcomes of the trial of randomized umbilical and fetal flow in Europe (TRUFFLE). Ultrasound in Obstetrics & Gynecology, 2013.PMID 24078432
  5. [5]Crispi F Long-term cardiovascular consequences of fetal growth restriction: biology, clinical implications, and opportunities for prevention from birth. American Journal of Obstetrics and Gynecology, 2018.PMID 29422215
  6. [6]Victora CG, Villar J, Barros FC, et al. Anthropometric characterization of impaired fetal growth: risk factors for and prognosis of newborns with stunting or wasting. JAMA Pediatrics, 2015.PMID 26147058
  7. [7]McKinlay CJ Neonatal glycemia and neurodevelopmental outcomes at 2 years. New England Journal of Medicine, 2015.PMID 26465984
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