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Paeds Vivasendocrinology-diabetes-and-growth

Paeds Vivas · endocrinology-diabetes-and-growth

Endocrine emergencies: integrated approach — branching viva

Branching viva on paediatric endocrine emergencies: recognising DKA, the cerebral injury watch, adrenal crisis in a child with known adrenal insufficiency, thyroid storm, hyponatraemic encephalopathy and diabetes insipidus after neurosurgery.

branching clinical structured oral3 min readSource-verified ·

Target exams

RACP General PaediatricsRACP DCEMRCPCH ClinicalRCPSC Pediatrics
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Study tools

Target exams

RACP General PaediatricsRACP DCEMRCPCH ClinicalRCPSC Pediatrics
Prompt
You are the paediatric registrar in the emergency department. Over a shift you see a 4-year-old in DKA, a 7-year-old with known adrenal insufficiency who is vomiting and drowsy, an adolescent with Graves disease, fever and tachycardia, a child with hyponatraemia who seizes, and a child after neurosurgery with rising sodium. The examiner releases information in stages.

Branch 1 — Recognising the hidden endocrine emergency

The examiner opens: which children in the emergency department should have a fingerstick glucose? The candidate cites ISPAD: DKA symptoms are non-specific, so consider a fingerstick glucose in all children with rapid breathing, or with vomiting and abdominal pain without diarrhoea. Emergency assessment then includes immediate glucose, ketones, electrolytes, blood gases and conscious level. [1]

The examiner asks for the definition of DKA. The candidate gives the three required criteria: glucose above 11 mmol/L, venous pH below 7.3 or bicarbonate below 18 mmol/L, and ketonaemia or ketonuria. [1]

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References8ShowHide
  1. [1]Glaser N, Fritsch M, Priyambada L, et al. ISPAD clinical practice consensus guidelines 2022: Diabetic ketoacidosis and hyperglycemic hyperosmolar state. Pediatric diabetes, 2022.PMID 36250645
  2. [2]Mushtaq T, Ali SR, Boulos N, et al. Emergency and perioperative management of adrenal insufficiency in children and young people: British Society for Paediatric Endocrinology and Diabetes consensus guidance. Archives of disease in childhood, 2023.PMID 37045585
  3. [4]Abisad DA, Glenn Lecea EM, Ballesteros AM, et al. Thyroid storm in pediatrics: a systematic review. Journal of pediatric endocrinology & metabolism : JPEM, 2023.PMID 36318760
  4. [5]Li X, Chen J, Li Z PICU treatment of 3 cases of pediatric thyroid storm: Case series and literature review. Medicine, 2023.PMID 37026965
  5. [6]Ayus JC, Moritz ML Misconceptions and Barriers to the Use of Hypertonic Saline to Treat Hyponatremic Encephalopathy. Frontiers in medicine, 2019.PMID 30931308
  6. [9]Driano JE, Lteif AN, Creo AL Vasopressin-Dependent Disorders: What Is New in Children? Pediatrics, 2021.PMID 33795481
  7. [12]Kuppermann N, Ghetti S, Schunk JE, et al. Clinical Trial of Fluid Infusion Rates for Pediatric Diabetic Ketoacidosis. The New England journal of medicine, 2018.PMID 29897851
  8. [13]Glaser N, Barnett P, McCaslin I, et al. Risk factors for cerebral edema in children with diabetic ketoacidosis. The Pediatric Emergency Medicine Collaborative Research Committee of the American Academy of Pediatrics. The New England journal of medicine, 2001.PMID 11172153
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