Paeds Vivas · allergy-and-immunology
Egg, wheat, soy, fish and shellfish allergy: Viva
Branching structured oral on paediatric egg, wheat, soy, fish and shellfish allergy: distinguishing IgE from non-IgE mechanisms, the signature allergen proteins and heat-stability, skin-prick and specific-IgE interpretation, component-resolved diagnostics, the baked-egg ladder, anaphylaxis treatment with intramuscular adrenaline, and the prognosis separating childhood-outgrown from lifelong allergens.
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Branch 1: Recognising and treating the acute event
The candidate should immediately recognise this as food-induced anaphylaxis. The rapid onset of urticaria with wheeze and hypotension minutes after eating a known allergen meets the clinical criteria for anaphylaxis, and the first action is intramuscular adrenaline into the anterolateral thigh. The single most important teaching point is that adrenaline must not be delayed for antihistamines, bronchodilators or observation, and that the combination of food allergy with uncontrolled asthma marks this boy as high-risk for a fatal outcome. [2]
The dose is the weight-appropriate autoinjector dose: at 14 years he is likely over 20 kg, so the 0.3 mg device is used, repeated after five minutes if there is no response. Adjuncts include high-flow oxygen, an inhaled bronchodilator for persistent wheeze, intravenous isotonic fluid for shock, and supine positioning with legs raised. The candidate should state that he needs hospital observation for a biphasic reaction, which can recur four to thirty hours later, and discharge with an adrenaline autoinjector, an action plan and allergy follow-up. [2]
References3ShowHide
- [1]Sicherer SH, Sampson HA Food allergy: Epidemiology, pathogenesis, diagnosis, and treatment. J Allergy Clin Immunol, 2014.PMID 24388012
- [2]Boyce JA, Assa'ad A, Burks AW, et al. Guidelines for the diagnosis and management of food allergy in the United States: report of the NIAID-sponsored expert panel. J Allergy Clin Immunol, 2010.PMID 21134576
- [3]Sicherer SH, Muñoz-Furlong A, Sampson HA Prevalence of seafood allergy in the United States determined by a random telephone survey. J Allergy Clin Immunol, 2004.PMID 15241360