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Paeds Vivasrespiratory-sleep-and-airway

Paeds Vivas · respiratory-sleep-and-airway

Congenital lung and airway malformations — structured oral (viva)

Branching structured oral on a large antenatally detected lung lesion progressing toward hydrops, testing antenatal risk stratification, fetal therapy, neonatal stabilisation and definitive surgery.

branching clinical structured oral2 min readVerification in progress

Target exams

RACP DCEMRCPCH ClinicalRCPSC Pediatrics
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Study tools

Target exams

RACP DCEMRCPCH ClinicalRCPSC Pediatrics
Prompt
A fetus at 22 weeks has a large solid-appearing lung lesion filling much of the right hemithorax with marked mediastinal shift. The referring unit is worried the fetus is developing early hydrops. The mother is otherwise well and this is her first pregnancy.

Branch 1 — Antenatal risk stratification

Examiner: "You are the fetal-medicine registrar. How do you decide how worried to be about this lesion?" Candidate: The raw size matters less than its physiological effect, so I focus on the mediastinal shift, the compression of the heart and great veins, and any early signs of hydrops such as skin oedema, ascites or a pericardial effusion. I would quantify the lesion using the CPAM volume ratio, a size index that predicts the risk of hydrops and directs how intensively the pregnancy is monitored, and I would follow it with serial ultrasound. A large solid microcystic lesion with a rising volume ratio and early hydrops marks this fetus as high risk. [1] [2]

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References4ShowHide
  1. [1]Pederiva F, Rothenberg SS, Hall N, et al Congenital lung malformations. Nat Rev Dis Primers, 2023.PMID 37919294
  2. [2]Kontopoulos E, Quintero LF, Quintero Kontopoulos A, et al Mathematical reappraisal of the congenital cystic adenomatoid malformation volume ratio. J Matern Fetal Neonatal Med, 2026.PMID 42010266
  3. [3]Peranteau WH, Boelig MM, Khalek N, et al Effect of single and multiple courses of maternal betamethasone on prenatal congenital lung lesion growth and fetal survival. J Pediatr Surg, 2016.PMID 26526208
  4. [4]Muntean A, Marsland L, Sikdar O, et al Neonatal Surgery for Congenital Lung Malformations: Indications, Outcomes and Association With Malignancy. J Pediatr Surg, 2025.PMID 40031114
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