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Paeds Vivasrheumatology-musculoskeletal-and-sports

Paeds Vivas · rheumatology-musculoskeletal-and-sports

Acute monoarthritis and septic arthritis — branching viva

Branching viva on acute monoarthritis and septic arthritis: applying the Kocher criteria, interpreting the synovial fluid, choosing the age-stratified empiric antibiotic, recognising the septic hip as a surgical emergency, and the culture-negative Kingella kingae presentation of the under-four.

branching clinical structured oral2 min readVerification in progress

Target exams

RACP DCEMRCPCH ClinicalRCPSC Pediatrics
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Study tools

Target exams

RACP DCEMRCPCH ClinicalRCPSC Pediatrics
Prompt
A three-year-old boy is carried in refusing to walk, holding his right hip flexed and externally rotated, with a fever of 39 degrees and raised inflammatory markers. The examiner asks: what is your differential, how do you apply the Kocher criteria, what is your single most important investigation, and what is your immediate management — then branches to the surgical emergency of the septic hip, the age-stratified empiric antibiotic, the culture-negative Kingella kingae in the younger child, the antimicrobial stewardship of narrowing and stepping down, and finally the neonate with a pseudoparalysed limb.

Branching framework

Open with the one-sentence problem representation. This is a febrile child with an acutely hot, held joint, and septic arthritis is the must-not-miss diagnosis until excluded by the synovial fluid. State the urgency aloud — cartilage destruction begins within hours, and the septic hip threatens the femoral head blood supply — before you discuss anything else. The examiner is listening for whether you reach for the aspiration and the theatre before you reach for the antibiotic. [1] [3]

Apply the Kocher criteria to estimate the probability. The four predictors are a fever above 38.5 degrees, an inability to bear weight, an ESR above 40, and a white cell count above 12,000, with the Caird addition of a CRP above 20 milligrams per litre. State the rising probability with each predictor, and be ready for the calibration probe — the Caird prospective study found the original Kocher probabilities may overestimate, so the criteria sharpen suspicion but never rule out sepsis. A child with two or more predictors warrants urgent aspiration. [1] [3]

Branch to the single most important investigation. The joint aspiration, under ultrasound guidance for the hip, sending the synovial fluid for a cell count above 50,000, a Gram stain, and culture, with blood-culture-bottle inoculation for Kingella kingae. State that the aspiration precedes the antibiotic, always, because an antibiotic given first sterilises the specimen. If the examiner probes a culture-negative result in the under-four, name Kingella kingae and the oropharyngeal swab PCR. [1] [7]

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References4ShowHide
  1. [1]Kocher MS, Zurakowski D, Kasser JR. Differentiating between septic arthritis and transient synovitis of the hip in children: an evidence-based clinical prediction algorithm. J Bone Joint Surg Am, 1999.PMID 10608376
  2. [3]Caird MS, Flynn JM, Leung YL, et al. Factors distinguishing septic arthritis from transient synovitis of the hip in children. A prospective study. J Bone Joint Surg Am, 2006.PMID 16757758
  3. [7]Ceroni D, Dubois-Ferriere V, Cherkaoui A, et al. Detection of Kingella kingae osteoarticular infections in children by oropharyngeal swab PCR. Pediatrics, 2013.PMID 23248230
  4. [9]Autore G, Bernardi L, Esposito S. Update on Acute Bone and Joint Infections in Paediatrics: A Narrative Review on the Most Recent Evidence-Based Recommendations and Appropriate Antinfective Therapy. Antibiotics (Basel), 2020.PMID 32781552
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