Paeds Vivas · gastroenterology-hepatology-and-nutrition
Acute gastroenteritis and infectious diarrhoea — branching viva
Branching viva from a toddler with watery diarrhoea and vomiting, through the clinical grading of dehydration, the mechanism of fluid loss and why oral rehydration solution works through the intact sodium-glucose co-transporter, the design of oral rehydration therapy and the place of nasogastric and intravenous fluids, the adjuncts of zinc and ondansetron, and a pivot to a child with bloody diarrhoea in whom antibiotics and haemolytic uraemic syndrome must be considered.
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Opening — framing the problem
The examiner begins: an 18-month-old has two days of watery diarrhoea and vomiting, is restless with sunken eyes and a slow skin pinch, but is alert with warm peripheries. Talk me through your approach. [1] [3]
I would frame this as acute gastroenteritis and make my first task the grading of dehydration, because that decides everything. The combination of sunken eyes, dry mucosa, a slow skin pinch and prolonged capillary refill in an alert child with warm peripheries fits some, or mild-to-moderate, dehydration rather than shock. I would rehydrate him orally while excluding a surgical mimic. [3] [1]
References6ShowHide
- [1]Guarino A; Ashkenazi S; Gendrel D; et al European Society for Pediatric Gastroenterology, Hepatology, and Nutrition/European Society for Pediatric Infectious Diseases evidence-based guidelines for the management of acute gastroenteritis in children in Europe: update 2014. J Pediatr Gastroenterol Nutr, 2014.PMID 24739189
- [3]Steiner MJ; DeWalt DA; Byerley JS Is this child dehydrated? JAMA, 2004.PMID 15187057
- [8]Lifschitz C; Kozhevnikov O; Oesterling C; et al Acute gastroenteritis-changes to the recommended original oral rehydrating salts: a review. Front Pediatr, 2023.PMID 38192370
- [5]Lazzerini M; Wanzira H Oral zinc for treating diarrhoea in children. Cochrane Database Syst Rev, 2016.PMID 27996088
- [11]Mwendera CA; Yilma M; Wairimu C; et al Burden of Shigella and enterotoxigenic Escherichia coli infections among children under 5 years in Ethiopia, Kenya and Malawi: a systematic review and meta-analysis. BMJ Glob Health, 2026.PMID 41771662
- [13]Freedman SB; Williamson-Urquhart S; Plint AC; et al Multidose Ondansetron after Emergency Visits in Children with Gastroenteritis. N Engl J Med, 2025.PMID 40673584