Paeds Vivas · paediatric-dermatology
Acne vulgaris in adolescents — branching viva
Branching viva on acne vulgaris in the adolescent: grading the comedonal versus the inflammatory disease, building the topical retinoid and benzoyl peroxide ladder with the antibiotic stewardship, branching to the oral isotretinoin with the pregnancy prevention and the cumulative dose, the acne fulminans emergency, and the hormonal female-pattern acne of the polycystic ovary syndrome.
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Target exams
Opening — grade and name the disease
Open with the severity and the comedonal versus the inflammatory split, because the split drives the treatment. This 15-year-old has the open and the closed comedones, the inflammatory papules and pustules, and a few tender nodules on the jawline and the upper back — the moderate inflammatory acne vulgaris with some nodular disease. I grade on a reproducible scale and I record the proportion of the comedonal to the inflammatory lesions, and my first move is the psychosocial screen, because his withdrawal from swimming is the distress signal the lesion count hides. [1] [9]
Branch 1 — the topical ladder
Walk the examiner through your topical regimen. The foundation is the topical retinoid, because it fixes the microcomedone upstream. I use the adapalene 0.1 per cent as a thin film to the whole affected area at night, with the benzoyl peroxide 2.5 per cent by day, and I choose the adapalene over the tretinoin because the adapalene is photostable and combines safely with the benzoyl peroxide whereas the tretinoin is degraded by it. I counsel the dryness, the photosensitivity, and the sunscreen, and I review at six to eight weeks. [1] [2]
Branch 2 — the antibiotic stewardship
Explain when and how you add the oral antibiotic. For the many papules and pustules I add the oral doxycycline once daily for three months, but never alone — it travels with the topical retinoid and the benzoyl peroxide. The stewardship rule is one fellowship tests every year: never the antibiotic monotherapy, always pair it with the benzoyl peroxide to limit the resistance, cap the oral course at three to four months, and let the retinoid carry the maintenance. I never combine the topical erythromycin with the topical clindamycin, because the cross-resistance gives no added benefit. [1] [7]
References5ShowHide
- [1]Reynolds RV, Yeung H, Cheng CE, et al. Guidelines of care for the management of acne vulgaris Journal of the American Academy of Dermatology, 2024.PMID 38300170
- [2]Eichenfield DZ, Sprague J, Eichenfield LF. Management of Acne Vulgaris: A Review JAMA, 2021.PMID 34812859
- [5]Bagatin E, Costa CS. The use of isotretinoin for acne - an update on optimal dosing, surveillance, and adverse effects Expert Review of Clinical Pharmacology, 2020.PMID 32744074
- [7]Zhu C, Wei B, Li Y, et al. Antibiotic resistance rates in Cutibacterium acnes isolated from patients with acne vulgaris: a systematic review and meta-analysis Frontiers in Microbiology, 2025.PMID 40535003
- [9]Gieler U, Gieler T, Kupfer JP. Acne and quality of life - impact and management Journal of the European Academy of Dermatology and Venereology, 2015.PMID 26059729