Paeds Cases · infectious-diseases
Tuberculosis in children — OSCE assessment and communication station
Observed structured encounter testing classification of childhood tuberculosis on the exposure-infection-disease spectrum, symptom-and-contact assessment, chest radiograph and Xpert MTB/RIF investigation interpretation, the 4-month SHINE regimen for non-severe disease and 6-month regimen for severe disease, emergency recognition of tuberculous meningitis, and the public-health duty of notification, contact tracing and source-case finding.
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Study tools
Target exams
OSCE \u2014 Assessment and communication station
Candidate instructions
You are the paediatric registrar. You have 8 minutes per station. [1]
Station A (classify, investigate and treat). A four-year-old boy is brought in thin, with a cough and intermittent fever for six weeks. His uncle was diagnosed with smear-positive pulmonary tuberculosis two weeks ago. His chest radiograph shows right paratracheal lymph-node enlargement without cavitation. Classify the child on the TB spectrum, outline the investigations, and explain the treatment plan to his mother through a trained interpreter. [1] [7]
Station B (TBM override and the contact). You are asked to review a two-year-old sibling of the same family who presents febrile, irritable and drowsy, and to counsel on an asymptomatic eight-month-old household contact. Recognise the emergency, outline immediate management, and explain contact screening and presumptive preventive therapy. [6] [1]
Examiner brief and marking domains
Domain 1 \u2014 Classification (Station A). Correctly places the child on the exposure-infection-disease spectrum as TB disease (symptoms plus a compatible radiograph), classifies the disease by site as intrathoracic and by severity as non-severe (lymph-node, non-cavitary, smear-negative pattern), and explains why the contact history is the most specific finding. [1] [3]
Domain 2 \u2014 Investigation (Station A). Outlines two to three early-morning gastric aspirates (or induced sputum) for Xpert MTB/RIF Ultra plus culture and susceptibility, a TST or IGRA to support infection, an HIV test, and a chest radiograph read for the lymph-node pattern. States clearly that a negative Xpert does not exclude disease and that treatment proceeds on a compatible picture. [5]
References5ShowHide
- [1]Perez-Velez CM, Marais BJ Tuberculosis in children. N Engl J Med, 2012.PMID 22830465
- [3]Marais BJ, Gie RP, Beyers N, et al A proposed radiological classification of childhood intra-thoracic tuberculosis. Pediatr Radiol, 2004.PMID 15300340
- [5]Kay AW, González Fernández L, Takwoingi Y, et al. Xpert MTB/RIF and Xpert MTB/RIF Ultra assays for active tuberculosis and rifampicin resistance in children. Cochrane Database Syst Rev, 2020.PMID 32853411
- [6]Seddon JA, Tugume L, Solomons R, et al The current global situation for tuberculous meningitis: epidemiology, diagnostics, treatment and outcomes. Wellcome Open Res, 2019.PMID 32118118
- [7]Turkova A, Wills GH, Wobudeya E, et al. Shorter Treatment for Nonsevere Tuberculosis in African and Indian Children. N Engl J Med, 2022.PMID 35263517