Paeds Cases · respiratory-sleep-and-airway
Pulmonary haemorrhage and haemoptysis — clinical case
Clinical case of an infant with recurrent occult alveolar haemorrhage, iron-deficiency anaemia, and faltering growth, illustrating the exclusion-based work-up, the diagnosis of Heiner syndrome, and cause-specific management.
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This infant presents with the occult face of pulmonary haemorrhage: recurrent cough and tachypnoea with pallor, an iron-deficiency anaemia that will not respond to iron, and shifting bilateral infiltrates, with only coffee-ground vomit rather than frank haemoptysis. The essential insight is that a young child swallows rather than coughs up blood, so recurrent alveolar bleeding masquerades as anaemia and breathlessness, and his cow-milk-based feeding immediately raises the possibility of a milk-driven cause. [3] [4]
References4ShowHide
- [1]Arasi S, Mastrorilli C, Pecoraro L, et al Heiner Syndrome and Milk Hypersensitivity: An Updated Overview on the Current Evidence. Nutrients, 2021.PMID 34070007
- [2]Moissidis I, Chaidaroon D, Vichyanond P, et al Milk-induced pulmonary disease in infants (Heiner syndrome). Pediatr Allergy Immunol, 2005.PMID 16176405
- [3]Saha BK Idiopathic pulmonary hemosiderosis: A state of the art review. Respir Med, 2021.PMID 33246295
- [4]Susarla SC, Fan LL Diffuse alveolar hemorrhage syndromes in children. Curr Opin Pediatr, 2007.PMID 17505192