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Paeds Casesfetal-neonatal-and-perinatal

Paeds Cases · fetal-neonatal-and-perinatal

Perinatal infection screening and prevention — case

Long case and communication station.

long case with communication2 min readVerification in progress

Target exams

RACP DCEMRCPCH Clinical
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Target exams

RACP DCEMRCPCH Clinical
Prompt
A GBS-colonised term infant with inadequate intrapartum prophylaxis and early respiratory distress, plus a hepatitis B risk to address.

Case summary

A term male is born at 39 weeks by spontaneous vaginal delivery after 18 hours of ruptured membranes. The mother is known to be Group B Streptococcus positive on a 36-week swab, but she received only one dose of intravenous benzylpenicillin two hours before delivery. Her booking antenatal screens were normal except that she is hepatitis B surface antigen positive. At four hours of age the infant is grunting, tachypnoeic (respiratory rate 72) and has cool peripheries and poor feeding. [1] [3]

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References4ShowHide
  1. [1]Schrag SJ Group B streptococcal disease in the era of intrapartum antibiotic prophylaxis. New England Journal of Medicine, 2000.PMID 10620644
  2. [3]Verani JR Prevention of perinatal group B streptococcal disease--revised guidelines from CDC, 2010. MMWR Recommendations and Reports, 2010.PMID 21088663
  3. [5]Stoll BJ Early-Onset Neonatal Sepsis 2015 to 2017, the Rise of Escherichia coli, and the Need for Novel Prevention Strategies. JAMA Pediatrics, 2020.PMID 32364598
  4. [9]Schillie S Prevention of Hepatitis B Virus Infection in the United States: Recommendations of the Advisory Committee on Immunization Practices. MMWR Recommendations and Reports, 2018.PMID 29939980
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