Paeds Cases · fetal-neonatal-and-perinatal
The cold preterm on admission — moderate hypothermia with hypoglycaemia
OSCE on a 28-week preterm infant who arrives in the neonatal unit at 35.0 C with a glucose of 1.6 mmol/L, testing the WHO classification, the four heat-loss pathways, the metabolic cascade, active external rewarming, glucose correction, and the delivery-room warm chain and plastic wrap.
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Clinical information for the examiner
Setting: Tertiary neonatal unit, 15 minutes after birth by emergency caesarean for preterm labour. The delivery room was noted to be cool (below 25 C). The infant was wrapped in a towel that is now damp. No plastic wrap was used; no hat was applied. [1]
On your arrival:
- Axillary temperature 35.0 C; infant is pale, grunting, with mild subcostal recession. [9]
- Heart rate 150, SpO₂ 90% in air, capillary refill 3 seconds, peripherally cool. [9]
- Bedside glucose 1.6 mmol/L. [9]
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References5Show ledgerHide ledger
- [1]Aziz K Part 5: Neonatal Resuscitation 2020 American Heart Association Guidelines for Cardiopulmonary Resuscitation and Emergency Cardiovascular Care. Pediatrics, 2021.PMID 33087555
- [3]McCall EM Interventions to prevent hypothermia at birth in preterm and/or low birth weight infants. Cochrane Database Syst Rev, 2018.PMID 29431872
- [4]Abiramalatha T Delivery Room Interventions for Hypothermia in Preterm Neonates: A Systematic Review and Network Meta-analysis. JAMA Pediatr, 2021.PMID 34028513
- [9]Hogeveen M Hypothermia and Adverse Outcomes in Very Preterm Infants: A Systematic Review. Pediatrics, 2025.PMID 40262762
- [10]Lamary M Neonatal Golden Hour: a review of current best practices and available evidence. Curr Opin Pediatr, 2023.PMID 36722754