Paeds Cases · genetics-dysmorphology-and-metabolism

Counsel parents given a prenatal diagnosis of 47,XXY Klinefelter syndrome — OSCE

OSCE communication and shared-planning station: counselling parents given a prenatal diagnosis of 47,XXY Klinefelter syndrome on cell-free DNA screening confirmed by amniocentesis. Explain the phenotype variability, the meaning of the karyotype, the limitations of the published literature, the lifespan surveillance framework, and the fertility prospects including micro-TESE, using balanced, non-directive, strengths-based language while addressing fear and avoiding deficit framing.