Paeds Cases · fetal-neonatal-and-perinatal
Intraventricular haemorrhage and periventricular leukomalacia — structured clinical encounter
Structured encounter testing the approach to a preterm infant with a sudden deterioration from a large intraventricular haemorrhage: recognition, Papile grading, immediate management, and the prevention and prognostic-counselling discussion.
On this page
Study tools
Target exams
Station brief (candidate)
You are the neonatal registrar. A 26-week-gestation infant, birthweight 760 g, is intubated and ventilated for respiratory distress syndrome. Antenatal steroids were given. At 36 hours of life, after a witnessed pneumothorax that required drainage, the infant has a sudden fall in haemoglobin from 145 to 88 g/L, a metabolic acidosis, a fall in blood pressure, and three brief focal seizures. The anterior fontanelle is bulging. The team asks you to establish the diagnosis and immediate management. You then proceed to the cranial-ultrasound result, the grading, the prevention discussion, and the prognostic counselling. You have 12 minutes with the team and 5 minutes for examiner discussion. [1]
References7ShowHide
- [1]Papile LA; Burstein J; Burstein R; Koffler H Incidence and evolution of subependymal and intraventricular hemorrhage: a study of infants with birth weights less than 1,500 gm. J Pediatr, 1978.PMID 305471
- [2]Ment LR; Oh W; Ehrenkranz RA; et al Low-dose indomethacin and prevention of intraventricular hemorrhage: a multicenter randomized trial. Pediatrics, 1994.PMID 8134206
- [3]Schmidt B; Roberts RS; Davis P; et al Caffeine therapy for apnea of prematurity. N Engl J Med, 2006.PMID 16707748
- [4]Rabe H; Gyte GM; Díaz-Rossello JL; Duley L Effect of timing of umbilical cord clamping and other strategies to influence placental transfusion at preterm birth on maternal and infant outcomes. Cochrane Database Syst Rev, 2019.PMID 31529790
- [5]Volpe JJ Dysmaturation of Premature Brain: Importance, Cellular Mechanisms, and Potential Interventions. Pediatr Neurol, 2019.PMID 30975474
- [6]Whitelaw A; Evans D; Carter M; et al Randomized clinical trial of prevention of hydrocephalus after intraventricular hemorrhage in preterm infants: brain-washing versus tapping fluid. Pediatrics, 2007.PMID 17403819
- [9]O'Shea TM; Kuban KC; Allred EN; et al Neonatal cranial ultrasound lesions and developmental delays at 2 years of age among extremely low gestational age children. Pediatrics, 2008.PMID 18762501