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Paeds Casesneurology-neurodisability-and-neuromuscular

Paeds Cases · neurology-neurodisability-and-neuromuscular

Headache and migraine in children: Case

Clinical case of a 14-year-old girl with chronic migraine and medication-overuse headache, covering the ICHD-3 diagnosis, the reversal of analgesic overuse, the acute abortive plan, and the stepped prophylaxis built on lifestyle and cognitive behavioural therapy in light of the CHAMP trial.

outpatient long case4 min readVerification in progress

Target exams

RACP DCEMRCPCH ClinicalRCPSC Pediatrics
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Target exams

RACP DCEMRCPCH ClinicalRCPSC Pediatrics
Prompt
A previously well 14-year-old girl is reviewed in the paediatric clinic for daily headache. Over the last four months she has had 18 or more headache days a month, mostly bilateral and throbbing with nausea and photophobia, and she has been taking ibuprofen and a combination paracetamol and codeine tablet on most days for the last two months. She has missed three weeks of school, has withdrawn from netball, and describes low mood. Her mother has migraine. Her blood pressure is 116 over 72, her fundi are normal with no papilloedema, her visual acuity and fields are normal, and her full neurological examination including gait is normal. There is no thunderclap, no occipital pain, no early-morning vomiting, and no focal deficit.

This girl has chronic migraine complicated by medication-overuse headache. Her headache pattern meets the ICHD-3 definition of chronic migraine, which is 15 or more headache days a month for over three months with at least eight migrainous days, and her attacks are bilateral, throbbing, and accompanied by nausea and photophobia, with a family history of migraine in her mother. Her daily use of ibuprofen and a combination paracetamol and codeine tablet over the last two months meets the threshold for medication-overuse headache, which is acute medication on 15 or more days a month for simple analgesics, or 10 or more days a month for combination analgesics, sustained for over three months. Her normal fundi, blood pressure, and neurological examination, and the absence of any red flag, confirm that this is a primary headache disorder rather than a secondary cause, so imaging is not indicated. [1]

Confirming the diagnosis and excluding a secondary cause

The first task is to confirm that this is a primary headache and to exclude a secondary cause. The history meets the ICHD-3 criteria for chronic migraine, and the deliberate red-flag screen is negative: there is no thunderclap onset, no occipital location, no focal deficit, no papilloedema, no early-morning vomiting, no progressive or under-five pattern, and no systemic features. Her blood pressure is normal, her fundi show no papilloedema, and her full neurological examination including gait and coordination is normal. On these grounds I would not arrange neuroimaging, because a primary headache that meets the criteria, with a negative red-flag screen and a normal examination, does not need a scan. The disability is substantial: she has missed three weeks of school, withdrawn from sport, and describes low mood, which I would quantify with the PedMIDAS to guide the intensity of the preventive plan. [1]

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References5ShowHide
  1. [1]Headache Classification Committee of the International Headache Society (IHS) The International Classification of Headache Disorders, 3rd edition. Cephalalgia, 2018.PMID 29368949
  2. [6]Powers SW, Coffey CS, Chamberlin LA, et al Trial of Amitriptyline, Topiramate, and Placebo for Pediatric Migraine. N Engl J Med, 2017.PMID 27788026
  3. [7]Powers SW, Kashikar-Zuck SM, Allen JR, et al Cognitive behavioral therapy plus amitriptyline for chronic migraine in children and adolescents: a randomized clinical trial. JAMA, 2013.PMID 24368463
  4. [8]Richer L, Billinghurst L, Linsdell MA, et al Drugs for the acute treatment of migraine in children and adolescents. Cochrane Database Syst Rev, 2016.PMID 27091010
  5. [12]Casanova A, Vives-Mestres M, Donoghue S, et al The role of avoiding known triggers, embracing protectors, and adhering to healthy lifestyle recommendations in migraine prophylaxis: Insights from a prospective cohort of 1125 people with episodic migraine. Headache, 2023.PMID 36651502
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