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Paeds Casesnephrology-urology-fluids-and-electrolytes

Paeds Cases · nephrology-urology-fluids-and-electrolytes

Haematuria: diagnostic approach — structured clinical encounter

Structured encounter testing the approach to a school-age child with cola-coloured urine two weeks after a sore throat: the glomerular versus non-glomerular fork, the recognition of post-streptococcal glomerulonephritis, the complement pattern, management of hypertension and fluid overload, and the safety-netting and follow-up decisions.

structured clinical encounter2 min readVerification in progress

Target exams

RACP General PaediatricsRACP DCEMRCPCH ClinicalRCPSC Pediatrics
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Target exams

RACP General PaediatricsRACP DCEMRCPCH ClinicalRCPSC Pediatrics
Prompt
A 7-year-old boy presents to a regional emergency department with cola-coloured urine, peri-orbital swelling and a headache, two weeks after a febrile sore throat. His blood pressure is at the ninety-fifth centile for age, sex and height, and the urine shows red-cell casts and proteinuria. You are the paediatric registrar working through recognition, resuscitation, investigation, definitive care and disposition.

Station 1 — recognition

The examiner asks what worries me about this child and how I frame the problem. I explain that cola-coloured urine with red-cell casts, dysmorphic red cells and proteinuria points to a glomerular source, and that the one to three week latency after a streptococcal throat infection points specifically to post-streptococcal glomerulonephritis. I confirm first that he is not in a hypertensive emergency, because his blood pressure is already at the limit and a nephritic child can deteriorate. I note that the colour and the cells together anchor the source before a single blood test returns. [8] [1]

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References4ShowHide
  1. [8]Duong MD; Reidy KJ Acute Postinfectious Glomerulonephritis. Pediatr Clin North Am, 2022.PMID 36880922
  2. [7]Iyengar A; Kamath N; Radhakrishnan J; et al Infection-Related Glomerulonephritis in Children and Adults. Semin Nephrol, 2023.PMID 38242806
  3. [1]Kallash M; Rheault MN Approach to Persistent Microscopic Hematuria in Children. Kidney360, 2020.PMID 35369549
  4. [6]Trimarchi H; Barratt J; Cattran DC; et al Oxford Classification of IgA nephropathy 2016: an update from the IgA Nephropathy Classification Working Group. Kidney Int, 2017.PMID 28341274
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