Paeds Cases · acute-care-resuscitation-and-toxicology
Fluid bolus therapy and vasoactive support — long case
A long case following a three-year-old in septic shock through aliquot-based crystalloid resuscitation with reassessment after each bolus, the transition to vasoactive support for fluid-refractory shock, cold versus warm shock phenotyping and agent selection, the FEAST caution in a rural setting, fluid overload recognition, and the structured handover to retrieval.
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Presentation
A three-year-old weighing 14 kilograms presents to a rural emergency department with fever for 12 hours, poor feeding, lethargy and a purpuric rash. The child is cool and mottled with weak central pulses, a capillary refill of 5 seconds, a heart rate of 175 per minute, a blood pressure of 68/42 mmHg and a reduced conscious state responding to voice. The hospital has intravenous access and crystalloid but no paediatric intensive care or vasoactive agents on site. Retrieval is available but transport time is 90 minutes. [4] [9]
References5ShowHide
- [1]Maitland K, Kiguli S, Opoka RO, et al. Mortality after fluid bolus in African children with severe infection The New England journal of medicine, 2011.PMID 21615299
- [2]Weiss, Scott L Surviving Sepsis Campaign International Guidelines for the Management of Sepsis and Septic Shock in Children 2026 Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies, 2026.PMID 41869844
- [3]Weiss, Scott L Surviving Sepsis Campaign International Guidelines for the Management of Septic Shock and Sepsis-Associated Organ Dysfunction in Children Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies, 2020.PMID 32032273
- [4]Bjorklund A, Resch J, Slusher T Pediatric Shock Review Pediatrics in review, 2023.PMID 37777656
- [9]Gupta S, Sankar J Advances in Shock Management and Fluid Resuscitation in Children Indian journal of pediatrics, 2023.PMID 36715864