Paeds Cases · neurology-neurodisability-and-neuromuscular
Explain the workup and the treatable-cause principle to the parents of a regressing adolescent — OSCE
OSCE communication and shared decision-making station: explaining to frightened parents that their adolescent's subacute psychiatric change, seizures, and movement disorder is developmental regression requiring an urgent workup, conveying the principle that a treatable autoimmune encephalitis must be excluded and treated early, managing uncertainty while keeping urgency, and outlining the diagnostic pathway and the support available.
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You are the paediatric registrar managing this adolescent on the ward. The task is to explain, in plain language, that the daughter's rapid change is a neurological problem called autoimmune encephalitis - a condition in which the immune system mistakenly attacks the brain - and that it is treatable when treatment is started early. You must convey honestly that a mental health presentation is one possibility but that the pattern of psychiatric change, seizures, and a movement disorder points to an inflammation of the brain that needs urgent investigation and treatment now, outline the workup and why a lumbar puncture and a scan are needed, and address the parents' fear and the relative's comment without dismissing them. Agree a clear next-step plan with a named contact and a follow-up. The consultation is ten minutes. [1] [2]
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- [1]Moeschler JB, Shevell M Comprehensive evaluation of the child with intellectual disability or global developmental delays. Pediatrics, 2014.PMID 25157020
- [2]Graus F, Titulaer MJ, Balu R, et al. A clinical approach to diagnosis of autoimmune encephalitis. Lancet Neurol, 2016.PMID 26906964
- [3]Cellucci T, Van Mater H, Graus F, et al. Clinical approach to the diagnosis of autoimmune encephalitis in the pediatric patient. Neurol Neuroimmunol Neuroinflamm, 2020.PMID 31953309