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O&G VivasAntenatal care — maternal immunisation

O&G Vivas · Antenatal care — maternal immunisation

Vaccination in pregnancy — structured oral station (12 minutes)

FRANZCOG oral-format station on vaccination in pregnancy: candidate states the four recommended vaccines and their timing, the contraindicated live vaccines, counsels a vaccine-hesitant woman with the evidence, and manages a seronegative result and an inadvertent exposure. Scored against the eight published RANZCOG oral domains.

clinical3 min readVerification in progress

Target exams

FRANZCOGMRCOGABOG
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Target exams

FRANZCOGMRCOGABOG
Prompt
You are the antenatal clinic registrar. A 26-year-old woman attends her booking visit at 12 weeks gestation. She is vaccine-hesitant and asks whether she 'really needs all those injections' in pregnancy. The examiner will probe your knowledge of the recommended vaccines, your counselling of a hesitant woman, and your management of a seronegative result and an inadvertent live-vaccine exposure.

Station format

4 minutes reading, 12 minutes examination, 20 marks, global scoring. The eight published RANZCOG oral domains apply to every station: history and examination; investigations and interpreting results; treatment and management; clinical knowledge; complex, urgent or unusual clinical presentations; rapport with patient, support person or colleague; respect; communication skills. You are being marked on how you behave, not only what you know. [4]

Reveal the examiner script and model responsesShowHide

Opening prompt — "She asks whether she really needs the injections. How do you respond?"

Model response — lead with rapport, then the four vaccines: [4]

  • "I would thank her for raising it and acknowledge that it is a reasonable question to think through. I would not pressure her — I would explain what is recommended and why, and support her to decide."
  • "There are four vaccines routinely recommended in pregnancy: influenza at any stage, pertussis around 20 to 32 weeks, COVID-19 per current guidance, and RSV around 28 to 36 weeks. Each protects both her and her baby — the antibodies she makes cross the placenta so her newborn is born already protected."[4]
  • "I would offer the influenza vaccine today if she is agreeable, and plan the others for the right visit."

Probe 1 — "Why pertussis in particular? Is it not a childhood disease?"

  • "Pertussis kills infants, and the deaths are concentrated in babies under three months — too young to have received their own vaccines. The maternal dose closes that gap. The Dabrera study found maternal pertussis vaccination was 93% effective in protecting infants under eight weeks."[2]
  • "That is why it is given in every pregnancy — the antibody wanes between pregnancies, and each baby needs its own fresh protection."[4]

Probe 2 — "She has heard vaccines are unsafe in pregnancy. What do you say?"

This is a scored communication domain. Demonstrate it out loud: [4]

  • "I would ask what specifically she has heard, and address it directly. The recommended vaccines in pregnancy are inactivated or recombinant — they cannot cause the infection. The live vaccines, like MMR and varicella, are genuinely not given in pregnancy, but the recommended ones are safe across all trimesters."[4]
  • "I would share the evidence: the COVID-19 mRNA studies show vaccination is associated with fewer, not more, pregnancy complications. Influenza vaccination has been used in pregnancy for decades."[5]
  • "I would offer her written information and time to decide, and record her decision either way."

Probe 3 — "Her booking serology comes back rubella IgG negative. What do you do?"

  • "I would not give MMR during pregnancy — it is a live vaccine and contraindicated. The reflex error is to vaccinate; the correct action is to defer."[4]
  • "I would plan MMR for the postpartum period, given before discharge. It is safe in breastfeeding. I would counsel her to avoid pregnancy for one month after the dose, and I would document the seronegative result and the plan."
  • "Rubella matters because primary infection in early pregnancy causes congenital rubella syndrome — so the postpartum catch-up is essential, not optional."[4]

Probe 4 — "She also tells you her GP gave her the MMR vaccine two weeks ago, before she knew she was pregnant. She is very anxious."

  • "I would reassure her. There is no documented link between inadvertent MMR in pregnancy and fetal harm, and termination is not recommended for the vaccine alone."[4]
  • "I would document the exposure, continue routine antenatal care, and make sure she understands this does not change her pregnancy management. The anxiety is the main thing to address here — with empathy and the evidence."[4]

Probe 5 — "Summarise your approach to vaccination in this pregnancy."

  • "Offer the four recommended vaccines at the right visits — influenza now, pertussis at 20 to 32 weeks, RSV at 28 to 36 weeks, COVID-19 per guidance. Defer MMR to postpartum given her seronegative status. Address her hesitancy with the evidence and the trusted-provider relationship. Document every vaccine given or declined, and report to the immunisation register."[4]
Obstetrics & Gynaecology Pro

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You have read the opening of this viva. The complete unit — every section and its primary-source references — is part of the Obstetrics & Gynaecology fellowship library.

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References5ShowHide
  1. [1]Zaman K, Roy E, Arifeen SE, et al. Effectiveness of maternal influenza immunization in mothers and infants N Engl J Med, 2008.PMID 18799552
  2. [2]Dabrera G, Amirthalingam G, Andrews N, et al. A case-control study to estimate the effectiveness of maternal pertussis vaccination in protecting newborn infants in England and Wales, 2012-2013 Clin Infect Dis, 2015.PMID 25332078
  3. [3]Kampmann B, Madhi SA, Munjal I, et al. Bivalent Prefusion F Vaccine in Pregnancy to Prevent RSV Illness in Infants N Engl J Med, 2023.PMID 37018474
  4. [4]American College of Obstetricians and Gynecologists ACOG Committee Opinion No. 741: Maternal Immunization Obstet Gynecol, 2018.PMID 29794683
  5. [5]Morgan JA, Biggio JR Jr, Martin JK, et al. Pregnancy Outcomes in Patients After Completion of the mRNA Coronavirus Disease 2019 (COVID-19) Vaccination Obstet Gynecol, 2023.PMID 36735413
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