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O&G TopicsUrogynaecology — fistula

O&G · Urogynaecology — fistula

Vesicovaginal and other urinary fistulae

Also known as VVF · Urogenital fistula · Genitourinary fistula · Ureterovaginal fistula · UVF · Vesicouterine fistula · Urethrovaginal fistula

Exam-exhaustive FRANZCOG fellowship reference on vesicovaginal and other urinary fistulae — the Goh and WHO/FIGO classifications, the obstetric versus iatrogenic versus radiation mechanism, the methylene blue dye test and indigo carmine discriminator, the 3-month timing rule for delayed repair, the vaginal Latzko and abdominal O'Connor approaches, and the Martius labial fat pad and gracilis muscle flap interposition options for complex, recurrent or irradiated fistulae. Globally tagged to MRCOG, ABOG, FRCSC and MRCPI.

medium16 referencesUpdated 28 July 202619 min readVerification in progress

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Target exams

FRANZCOGMRCOGABOGFRCSCMRCPI

Red flags

  • Continuous urinary leakage per vagina day and night from day 1 after pelvic surgery — iatrogenic VVF or ureterovaginal fistula until proven otherwise; do not label as stress incontinence
  • Post-hysterectomy patient with continuous leakage and apparently normal voiding — high probability of ureterovaginal fistula; image upper tracts with CT urogram before any repair
  • Anuria after hysterectomy or radical pelvic surgery — bilateral ureteric injury until proven otherwise; decompress and image urgently
  • Failed primary fistula repair with persistent leakage — never re-operate within 3 months; obtain CT urogram and cystoscopy, plan interposition at the next attempt
  • Fistula in a patient with prior pelvic radiotherapy — tissue ischaemic and fibrotic; primary closure without interposition (Martius or gracilis) has very high failure
  • Combined vesicovaginal and rectovaginal fistula after obstructed labour or radiation — staged repair with colorectal input, do not promise continence
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Your progress

Saved on this device.

Practise this topic8 MCQs with explanations

Target exams

FRANZCOGMRCOGABOGFRCSCMRCPI

Red flags

  • Continuous urinary leakage per vagina day and night from day 1 after pelvic surgery — iatrogenic VVF or ureterovaginal fistula until proven otherwise; do not label as stress incontinence
  • Post-hysterectomy patient with continuous leakage and apparently normal voiding — high probability of ureterovaginal fistula; image upper tracts with CT urogram before any repair
  • Anuria after hysterectomy or radical pelvic surgery — bilateral ureteric injury until proven otherwise; decompress and image urgently
  • Failed primary fistula repair with persistent leakage — never re-operate within 3 months; obtain CT urogram and cystoscopy, plan interposition at the next attempt
  • Fistula in a patient with prior pelvic radiotherapy — tissue ischaemic and fibrotic; primary closure without interposition (Martius or gracilis) has very high failure
  • Combined vesicovaginal and rectovaginal fistula after obstructed labour or radiation — staged repair with colorectal input, do not promise continence
One-line fellowship answer

A urogenital fistula is an abnormal communication between the urinary tract and vagina — most commonly vesicovaginal (VVF), then ureterovaginal (UVF) and urethrovaginal; classify by the Goh four-item staging (size, site, aetiology, scarring) and the WHO/FIGO surgical type, diagnose with the methylene blue dye test (blue leakage = VVF; clear leakage with blue bladder = UVF), image upper tracts with CT urogram, wait at least 3 months from injury for delayed repair (or 1–2 weeks for a clean post-operative field), match approach to location — vaginal Latzko for simple supratrigonal, abdominal O'Connor for trigonal or retropubic, and add Martius or gracilis interposition for irradiated, recurrent or large (>3 cm) fistulae.[1][2][4][7][8]

It is a Tuesday morning in the urogynaecology clinic. A 34-year-old teacher sits down in wet clothes and says, without preamble, "I leak all day and all night — since my hysterectomy eight weeks ago." She has been wearing pads continuously. Her MSU is sterile. Her previous surgeon told her it was "just stress incontinence." It is not stress incontinence — it is a vesicovaginal fistula until proven otherwise, and the next steps are an examination, a dye test, an upper-tract image, and a date for repair in about 3 months' time. The art is to recognise the pattern, name the operation you will offer, and not waste the first attempt.[4][11]

Overview and definition

A genitourinary fistula is an abnormal communication between the urinary tract (bladder, ureter, urethra) and the female genital tract. The vast majority are vesicovaginal fistulae (VVF) — a tract from the bladder to the vagina through which urine leaks continuously. A ureterovaginal fistula (UVF) connects a ureter to the vagina and is the second commonest; urethrovaginal and vesicouterine fistulae are uncommon.[4][11]

The clinical signature is continuous urinary leakage per vagina, day and night, with no dry interval between voids — the bladder is no longer a closed reservoir, and any rise in intravesical pressure (cough, walk, supine) drives urine through the tract. The pad is soaked continuously; the underlying bedding is wet; the woman smells of urine despite multiple pad changes a day.[4][11]

VVF is broadly two diseases:[2][4][11][15]

  • Obstetric fistula — the global burden; caused by prolonged obstructed labour with pressure necrosis of the bladder base, urethra and anterior vaginal wall. Predominant in low- and middle-income countries (LMIC) where women labour without access to caesarean section. Often very large, with urethral destruction, scarring and a cohort of psychosocial morbidity (stillbirth, divorce, social isolation).[2][15]
  • Iatrogenic fistula — the dominant mechanism in high-income countries (HIC); caused by pelvic surgery, most commonly total abdominal hysterectomy (TAH), laparoscopic hysterectomy, radical hysterectomy for cervical cancer, or anterior colporrhaphy. Often small, accessible in the vault, and the operative field is clean.[4][11]
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References16ShowHide
  1. [1]Goh JT A new classification for female genital tract fistula Aust N Z J Obstet Gynaecol, 2004.PMID 15598284
  2. [2]Goh JT, Browning A, Berhan B, Chang A Predicting the risk of failure of closure of obstetric fistula and residual urinary incontinence using a classification system Int Urogynecol J, 2008.PMID 18690403
  3. [3]Goh JT, Krause HG, Browning A, Chang A Classification of female genito-urinary tract fistula: Inter- and intra-observer correlations Int Urogynecol J, 2009.PMID 19215564
  4. [4]Thayalan K, Parghi S, Krause H, Goh J Vesicovaginal fistula following pelvic surgery: Our experiences and recommendations for diagnosis and prompt referral Aust N Z J Obstet Gynaecol, 2020.PMID 32083317
  5. [5]Hanash KA, Al Zahrani H, Mokhtar AA, Aslam M Retrograde vaginal methylene blue injection for localization of complex urinary fistulas J Urol, 2003.PMID 14744368
  6. [6]Kajabwangu R, Geissbüehler V, Tibaijuka L, et al. The Management of Iatrogenic Ureterovaginal Fistula in a Resource-Limited Setting: A 12-Year Experience at Four Fistula Surgery Centers in Uganda Int Urogynecol J, 2024.PMID 39840170
  7. [7]Luo DY, Shen H Transvaginal Repair of Apical Vesicovaginal Fistula: A Modified Latzko Technique — Outcomes at a High-volume Referral Center Urology, 2019.PMID 31064690
  8. [8]Dorairajan LN, Khattar N, Kumar S, Pal BC Latzko repair for vesicovaginal fistula revisited in the era of minimal-access surgery Int Urogynecol J, 2008.PMID 17885818
  9. [9]Sharma S, Rizvi SJ, Bethur SS, Bansal J, Qadri SJ, Modi P Laparoscopic repair of urogenital fistulae: A single centre experience Indian J Urol, 2014.PMID 25336817
  10. [10]Choudhury S, Biswas P, Patel P, Sasmal S, Ahmed S Use of fibrin glue versus martius flap interposition in Trans-vaginal vesicovaginal fistula repair: A prospective randomized trial Int Urogynecol J, 2026.PMID 41688883
  11. [11]Klemm J, Stelzl DR, Schulz RJ, et al. Female non-obstetric urogenital fistula repair: long-term patient-reported outcomes and a scoping literature review Int Urogynecol J, 2024.PMID 38733321
  12. [12]Kołodyńska A, Streit-Ciećkiewicz D, Kot A, Kuliniec I, Futyma K Radiation-Induced Recurrent Vesicovaginal Fistula — Treatment with Adjuvant Platelet-Rich Plasma Injection and Martius Flap Placement — Case Report and Review of Literature J Clin Med, 2021.PMID 34063610
  13. [13]Ayed M, El Atat R, Hassine LB, Sfaxi M, Chebil M, Zmerli S Prognostic factors of recurrence after vesicovaginal fistula repair Tunis Med, 2006.PMID 16734848
  14. [14]Kabore M, Ziba OJD, Yameogo CAMKD, et al. Risk factors for developing residual stress urinary incontinence after vesico-vaginal fistula repair: A retrospective cohort study Int Urogynecol J, 2024.PMID 39461725
  15. [15]Maljaars LP, Hesham H, Huisman H, Nundwe W, Roovers JWR, Pope RJ Predictors of outcomes in patients with repeat surgery for obstetric fistula: a retrospective review Int Urogynecol J, 2023.PMID 36607397
  16. [16]Hwang JH, Kim B Postoperative Urinary Complications in Minimally Invasive Versus Abdominal Radical Hysterectomy: A Meta-Analysis With a Focus on Ureterovaginal Fistula Ann Surg Oncol, 2025.PMID 39710105

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