O&G · Perioperative care — post-operative complications
Post-operative complications in gynaecological surgery
Also known as Post-op complications · Surgical complications · Post-operative morbidity · Surgical site infection · Anastomotic leak · Paralytic ileus · Wound dehiscence · Post-operative haemorrhage · Post-operative VTE · Post-operative sepsis
Exam-exhaustive FRANZCOG fellowship reference on post-operative complications in gynaecological surgery: paralytic ileus, anastomotic leak, wound dehiscence and surgical site infection, secondary haemorrhage, venous thromboembolism, urinary retention; the sepsis screen (qSOFA, NEWS2) and the hour-1 bundle; the indications for reoperation and the Clavien-Dindo severity grading. RANZCOG-primary, globally tagged to MRCOG and ABOG.
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Target exams
Red flags
- Tachycardia out of proportion to the wound on day 5-8 — think anastomotic leak, not 'slow recovery'
- A single NEWS2 score of 7 or more — senior review immediately, not a sigh
- Persistent NEWS2 score of 5 or 6, or two consecutive scores rising — speak to the consultant
- New foot drop on PACU review — common peroneal nerve injury, document and refer, not 'wait and see'
- Wound evisceration — sterile saline-soaked gauze, return to theatre within hours
- Calves swollen or breathlessness after discharge — VTE until proven otherwise, even on prophylaxis
It is 02:30 on the gynaecology ward. The post-op hysterectomy you have just taken over is day 5, the patient has been afebrile and "stable" for the morning round, and the nurse hands you the observation chart with a quiet word: "she's not quite right." Pulse 108, RR 22, blood pressure 104/68, temperature 37.9. NEWS2 is 6. The wound looks pink, the abdomen is soft, but the drain fluid that was serous yesterday is now muddy, and the patient has not opened her bowels since day 2. The diagnosis is already in the room — anastomotic leak, day 5, the classic presentation. The next ten minutes decide whether she goes to CT and survives, or to HDU and does not. This topic is that rehearsal.[1][4][19]
Overview and definition
Complications are the second half of the surgical episode. The first half is the operation; the second half is the recovery; both belong to the surgeon. The post-operative period partitions naturally by time, and the differential changes with the clock. [1]
- Immediate (0–24 h): primary haemorrhage, reactional haemorrhage (24–48 h), emergence agitation, opioid-induced respiratory depression, anaphylaxis, hypothermia, vasovagal collapse.
- Early (24 h to 7 days): ileus, urinary retention, ileus vs early small-bowel obstruction, wound haematoma, seroma, urinary tract infection, Clostridium difficile, pneumonia, retained swab/instrument.
- Intermediate (5–14 days): the classic window for wound infection, fascial dehiscence, anastomotic leak (peak day 5–8), intra-abdominal collection, secondary haemorrhage, VTE.
- Late (after 14 days): late wound complications, port-site hernia, adhesive obstruction, chronic pain, lymphoedema, anastomotic stricture, recurrence in oncology.
The Clavien-Dindo classification is the modern common language. Reproduce it cold when the examiner asks for an example. [19]
| Grade | Trigger | Example |
|---|---|---|
| I | Any deviation from normal post-op course; allowed therapeutic regimens | Wound infection opened at bedside |
| II | Requires pharmacological treatment | Blood transfusion, IV antibiotics for UTI |
| IIIa | Surgical/endoscopic/radiological intervention, no GA | Drainage of pelvic collection under LA |
| IIIb | Intervention under GA | Return to theatre for wound dehiscence |
| IVa | Life-threatening ICU; single organ dysfunction | Dialysis, ventilation |
| IVb | Multi-organ dysfunction | Multi-organ failure |
| V | Death | — |
References20ShowHide
- [1]Nelson G, Bakkum-Gamez J, Kalogera E, et al. Guidelines for perioperative care in gynecologic/oncology: Enhanced Recovery After Surgery (ERAS) Society recommendations-2019 update Int J Gynecol Cancer, 2019.PMID 30877144
- [2]Gustafsson UO, Scott MJ, Hubner M, et al. Guidelines for Perioperative Care in Elective Colorectal Surgery: Enhanced Recovery After Surgery (ERAS®) Society Recommendations: 2018 World J Surg, 2019.PMID 30426190
- [3]Wijk L, Udumyan R, Pache B, et al. International validation of Enhanced Recovery After Surgery Society guidelines on enhanced recovery for gynecologic surgery Am J Obstet Gynecol, 2019.PMID 31051119
- [4]Williams B The National Early Warning Score: from concept to NHS implementation Clin Med (Lond), 2022.PMID 36427887
- [5]Smith GB, Prytherch DR, Meredith P, et al. The ability of the National Early Warning Score (NEWS) to discriminate patients at risk of early cardiac arrest, unanticipated intensive care unit admission, and death Resuscitation, 2013.PMID 23295778
- [6]Singer M, Deutschman CS, Seymour CW, et al. The Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3) JAMA, 2016.PMID 26903338
- [7]Rhodes A, Evans LE, Alhazzani W, et al. Surviving Sepsis Campaign: International Guidelines for Management of Sepsis and Septic Shock: 2016 Intensive Care Med, 2017.PMID 28101605
- [8]Evans L, Rhodes A, Alhazzani W, et al. Executive Summary: Surviving Sepsis Campaign: International Guidelines for the Management of Sepsis and Septic Shock 2021 Crit Care Med, 2021.PMID 34643578
- [9]Peake SL, Delaney A, Bailey M, et al. Goal-directed resuscitation for patients with early septic shock N Engl J Med, 2014.PMID 25272316
- [10]Rowan KM, Angus DC, Bailey M, et al. Early, Goal-Directed Therapy for Septic Shock - A Patient-Level Meta-Analysis N Engl J Med, 2017.PMID 28320242
- [11]Holst LB, Haase N, Wetterslev J, et al. Lower versus higher hemoglobin threshold for transfusion in septic shock N Engl J Med, 2014.PMID 25270275
- [12]WOMAN Trial Collaborators Effect of early tranexamic acid administration on mortality, hysterectomy, and other morbidities in women with post-partum haemorrhage (WOMAN): an international, randomised, double-blind, placebo-controlled trial Lancet, 2017.PMID 28456509
- [13]Bratzler DW, Dellinger EP, Olsen KM, et al. Clinical practice guidelines for antimicrobial prophylaxis in surgery Surg Infect (Larchmt), 2013.PMID 23461695
- [14]Royal College of Obstetricians and Gynaecologists (RCOG) Prevention and Management of Postpartum Haemorrhage: Green-top Guideline No. 52 BJOG, 2017.PMID 27981719
- [15]Chui J, Murkin JM, Posner KL, et al. Perioperative Peripheral Nerve Injury After General Anesthesia: A Qualitative Systematic Review Anesth Analg, 2018.PMID 29787414
- [16]Grant I, Brovman EY, Kang D, et al. A medicolegal analysis of positioning-related perioperative peripheral nerve injuries occurring between 1996 and 2015 J Clin Anesth, 2019.PMID 31128482
- [17]Lasocki S, Pène F, Ait-Oufella H, et al. Management and prevention of anemia (acute bleeding excluded) in adult critical care patients Anaesth Crit Care Pain Med, 2020.PMID 32713688
- [18]Escobar MF, Nassar AH, Theron G, et al. FIGO recommendations on the management of postpartum hemorrhage 2022 Int J Gynaecol Obstet, 2022.PMID 35297039
- [19]Clavien PA, Barkun J, de Oliveira ML, et al. The Clavien-Dindo classification of surgical complications: five-year experience Ann Surg, 2009.PMID 19638912
- [20]Committee on Practice Bulletins-Obstetrics Practice Bulletin No. 183: Postpartum Hemorrhage Obstet Gynecol, 2017.PMID 28937571