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O&G TopicsGynaecological surgery — intraoperative complications and lower urinary tract injury

O&G · Gynaecological surgery — intraoperative complications and lower urinary tract injury

Recognition and intraoperative management of ureteric and bladder injury

Also known as Ureteric injury · Ureteral injury · Bladder injury · Cystotomy · Lower urinary tract injury · Iatrogenic urinary tract injury · Vesicovaginal fistula · Ureterovaginal fistula

Exam-exhaustive FRANZCOG fellowship reference on recognising and repairing ureteric and bladder injury during gynaecological surgery — the points where the pelvic ureter is at risk, bladder and trigone relations, intraoperative recognition with cystoscopy (sensitivity 80-90 percent for ureteral trauma), intraureteral ICG, indigo carmine and sodium fluorescein, the repair ladder by ureteric level (ureteroureterostomy, ureteroneocystostomy, psoas hitch, Boari flap), incidental cystotomy repair, management success rates and the medicolegal weight of delayed recognition. RANZCOG-primary, globally tagged to MRCOG, ABOG and FRCSC.

high22 referencesUpdated 1 Aug 202623 min readVerification in progress

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Target exams

FRANZCOGMRCOGABOGFRCSCMRCPI

Red flags

  • Absent ureteric jet on cystoscopy after a difficult dissection — the single best intraoperative warning of ureteric injury
  • An ureter that looks intact beside an energy device — thermal injury necroses days later, debride beyond the visible burn
  • Fever, ileus and flank pain in the first postoperative week — a missed ureteric or bladder injury until proven otherwise
  • Continuous vaginal urinary leakage after hysterectomy — vesicovaginal or ureterovaginal fistula
  • Anuria or rapidly rising creatinine postoperatively — bilateral ureteric injury until excluded by imaging
  • A prophylactic ureteric catheter in situ — it does NOT prevent injury, it only aids recognition; never be falsely reassured
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Your progress

Saved on this device.

Practise this topic10 MCQs with explanations

Target exams

FRANZCOGMRCOGABOGFRCSCMRCPI

Red flags

  • Absent ureteric jet on cystoscopy after a difficult dissection — the single best intraoperative warning of ureteric injury
  • An ureter that looks intact beside an energy device — thermal injury necroses days later, debride beyond the visible burn
  • Fever, ileus and flank pain in the first postoperative week — a missed ureteric or bladder injury until proven otherwise
  • Continuous vaginal urinary leakage after hysterectomy — vesicovaginal or ureterovaginal fistula
  • Anuria or rapidly rising creatinine postoperatively — bilateral ureteric injury until excluded by imaging
  • A prophylactic ureteric catheter in situ — it does NOT prevent injury, it only aids recognition; never be falsely reassured
One-line fellowship answer

Iatrogenic ureteric and bladder injury is governed by two rules: know the points where the pelvic ureter is at risk — at the infundibulopelvic ligament, the ovarian fossa, the uterine artery crossover, and the ureteric tunnel — and confirm the integrity of both ureters and the bladder before you close, by cystoscopy with dye jets (sensitivity around 80 to 90 percent for ureteral trauma), intraureteral ICG, or retrograde pyelogram. A bladder cystotomy is repaired in two absorbable layers and drained by catheter; a ureteric injury is repaired by level — ureteroureterostomy over a stent for mid loss, ureteroneocystostomy with a psoas hitch or Boari flap for distal loss — always with viable margins, tension-free, over a stent and drained. A systematic review of 1517 patients reports an 87 percent pooled clinical success rate, with renal unit loss in only 2.3 percent — but that good outcome belongs to the injury you recognise and repair intraoperatively; the missed one is a fistula, a lost kidney, and a lawsuit.[1][4][15]

You are doing a laparoscopic hysterectomy for a bulky fibroid uterus in a woman with deep endometriosis. The left ureter was hard to find all morning. You fired the bipolar across the cardinal ligament, and now there is an unsettling quiet where a jet should be. This is the moment that separates the fellowship registrar from the defendant — not the injury itself, which happens to competent surgeons, but whether you recognise it now, in the light, with the team beside you, or whether you discover it on day five when she leaks urine vaginally and her creatinine climbs. Lower urinary tract (LUT) injury rewards the surgeon who looks for it and punishes the one who assumes.[1][3]

Overview and definition

Iatrogenic LUT injury is damage to the ureter or bladder sustained during pelvic surgery. The two are spoken of together but are different problems in incidence, recognition and consequence. [1][2]

  • Bladder injury (cystotomy): commoner, more often obvious, and forgiving when repaired at once — a cut or tear of the bladder wall, most often the dome during dissection of the vesicouterine space or at port and Veress entry.[1][10]
  • Ureteric injury: far less common than bladder injury but far more often missed, and the source of most of the litigation, the fistulae and the lost kidneys in this field.[2][3]

The definition that matters clinically is by timing of recognition: an injury found and repaired during the index operation is immediate; one found afterwards is delayed. The EAU systematic review of 1517 iatrogenic ureteric injuries stratified outcome by exactly this — the timing and modality of management — and timing is what drives renal salvage: recognised intraoperatively, a ureteric injury repaired by the book carries the success of elective reconstructive surgery; missed, it causes fistula, urinoma, hydronephrosis, sepsis and renal loss.[1][15]

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References22ShowHide
  1. [1]Teeluckdharry B, Gilmour D, Flowerdew G Urinary Tract Injury at Benign Gynecologic Surgery and the Role of Cystoscopy: A Systematic Review and Meta-analysis Obstet Gynecol, 2015.PMID 26551173
  2. [2]Gilmour DT, Das S, Flowerdew G Rates of urinary tract injury from gynecologic surgery and the role of intraoperative cystoscopy Obstet Gynecol, 2006.PMID 16738165
  3. [3]Gilmour DT, Dwyer PL, Carey MP Lower urinary tract injury during gynecologic surgery and its detection by intraoperative cystoscopy Obstet Gynecol, 1999.PMID 10546778
  4. [4]AAGL Advancing Minimally Invasive Gynecology Worldwide AAGL Practice Report: Practice guidelines for intraoperative cystoscopy in laparoscopic hysterectomy J Minim Invasive Gynecol, 2012.PMID 22748947
  5. [5]American College of Obstetricians and Gynecologists ACOG Committee Opinion No. 372: The Role of cystourethroscopy in the generalist obstetrician-gynecologist practice Obstet Gynecol, 2007.PMID 17601926
  6. [6]Gurumurthy M, McGee AE, Saraswat L Prophylactic ureteric catheterisation during complex gynaecological surgery: A systematic review and meta-analysis BJOG, 2024.PMID 38602151
  7. [7]Zhang V, Mantri D, Yang Q, Guan X Indocyanine green for intraoperative ureteral identification in gynecologic surgery: A preliminary systematic review of feasibility, safety, and surgical outcomes Int J Gynaecol Obstet, 2026.PMID 42007650
  8. [8]Doyle PJ, Lipetskaia L, Duecy E, Buchsbaum G, Wood RW Sodium fluorescein use during intraoperative cystoscopy Obstet Gynecol, 2015.PMID 25730214
  9. [9]Wang Z, Chen Z, He Y, Li B, Wen Z, Chen X Laparoscopic ureteroureterostomy with an intraoperative retrograde ureteroscopy-assisted technique for distal ureteral injury secondary to gynecological surgery: a retrospective comparison with laparoscopic ureteroneocystostomy Scand J Urol, 2017.PMID 28388304
  10. [10]Brummer TH, Jalkanen J, Fraser J, Heikkinen AM, Kauko M, Mäkinen J, Seppälä T, Sjöberg J, Tomás E, Härkki P FINHYST, a prospective study of 5279 hysterectomies: complications and their risk factors Hum Reprod, 2011.PMID 21540244
  11. [11]Gellhaus PT, Bhandari A, Monn MF, Gardner TA, Kanagarajah P, Reilly CE, Llukani E, Lee Z, Eun DD, Rashid H, Joseph JV, Ghazi AE, Wu G, Boris RS Robotic management of genitourinary injuries from obstetric and gynaecological operations: a multi-institutional report of outcomes BJU Int, 2015.PMID 24750903
  12. [12]Ahmad G, Baker J, Finnerty J, Phillips K, Watson A Laparoscopic entry techniques Cochrane Database Syst Rev, 2019.PMID 30657163
  13. [13]Morey AF, Broghammer JA, Hollowell CMP, McKibben MJ, Souter L Urotrauma Guideline 2020: AUA Guideline J Urol, 2021.PMID 33053308
  14. [14]McMillan E, Meepagala S, Ogbutor K, Monroe D, Gibbs T, Wheaton N, Ramkissoon NR, Zinabu SW, Michael MB Prevalence of Serotonergic Drug Use in Patients Exposed to Perioperative Methylene Blue: A Cross-Sectional Study Cureus, 2025.PMID 40271333
  15. [15]Scilipoti P, Nannola N, Zorzi F, Gonzalez CG, Chicaud M, Candela L, Moretto S, Nedbal C, Tefik T, Villa L, Ventimiglia E, Salonia A, Briganti A, Montorsi F, Somani BK, Doizi S, Traxer O, Panthier F Iatrogenic ureteric injuries after abdominal surgery: a systematic review and meta-regression from the European Association of Urology Endourology Section BJU Int, 2026.PMID 42023813
  16. [16]Sokol AI, Paraiso MF, Cogan SL, Bedaiwy MA, Escobar PF, Barber MD Prevention of vesicovaginal fistulas after laparoscopic hysterectomy with electrosurgical cystotomy in female mongrel dogs Am J Obstet Gynecol, 2004.PMID 15041991
  17. [17]Nezhat CH, Seidman DS, Nezhat F, Rottenberg H, Nezhat C Laparoscopic management of intentional and unintentional cystotomy J Urol, 1996.PMID 8808881
  18. [18]Alabousi A, Patlas MN, Menias CO, Dreizin D, Bhalla S, Hon M, O'Brien A, Katz DS Multi-modality imaging of the leaking ureter: why does detection of traumatic and iatrogenic ureteral injuries remain a challenge? Emerg Radiol, 2017.PMID 28451770
  19. [19]Tarney CM Bladder Injury During Cesarean Delivery Curr Womens Health Rev, 2013.PMID 24876830
  20. [20]Keles A, Hamid-Zada I, Arikan O, Dalgic G, Durmaz AS, Keles E, Karakeci A, Bicaklioglu F, Gungor HS, Baydili KN, Eryildirim B, Kucuk EV, Yildirim A Management of urological injuries following gynecologic and obstetric surgery: A retrospective multicenter study Northern Clinics of Istanbul, 2024.PMID 39165709
  21. [21]Carbone L, Seymour K, Rothenberger R, Lenger SM, Francis S, Gupta A Indocyanine Green Ureteral Mapping in Complex Pelvic Surgery Int Urogynecol J, 2025.PMID 40261355
  22. [22]Robin F, Roux L, Zaheer MA, Sulpice L, Dion L, Lavoue V, Landreau J, Morandi X, Nyangoh Timoh K A reappraisal of the deep uterine vein: a multimodal exploration with implications for pelvic surgery Surg Radiol Anat, 2024.PMID 38493417

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