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O&G TopicsGynae-surgery — cervical insufficiency and preterm birth prevention

O&G · Gynae-surgery — cervical insufficiency and preterm birth prevention

Abdominal and transvaginal cervical cerclage

Also known as Cervical cerclage · Cervical stitch · McDonald suture · Shirodkar suture · Transabdominal cerclage · Rescue cerclage · Cerclage for cervical insufficiency

Exam-exhaustive FRANZCOG fellowship reference on cervical cerclage — history-, ultrasound- and examination-indicated indications; McDonald vs Shirodkar; transabdominal cerclage (open and laparoscopic) for failed vaginal cerclage; rescue cerclage; suture material (C-STICH); PPROM and removal; and the landmark RCTs and meta-analyses (MRC/RCOG, To, Berghella, MAVRIC). RCOG Green-top Guideline No. 75 (2022)-aligned, globally tagged to MRCOG and ABOG.

high12 referencesUpdated 1 Aug 202610 min readVerification in progress

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Target exams

FRANZCOGMRCOGABOGFRCSCMRCPI

Red flags

  • Painless cervical dilation with membranes visible at the os in the second trimester — rescue cerclage territory, but only after excluding infection and labour
  • A short cervix in a woman with a prior spontaneous preterm birth before 24 weeks — the best-evidenced responder; do not watch and wait
  • Fever, uterine tenderness or tachycardia with a stitch in situ — chorioamnionitis: the stitch fails and harms in an infected uterus
  • A previously failed vaginal cerclage presenting again — this is the woman to offer transabdominal cerclage next, not another vaginal stitch
  • Cerclage in a multiple pregnancy — not routine; benefit is small or absent and harm is possible
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Your progress

Saved on this device.

Practise this topic8 MCQs with explanations

Target exams

FRANZCOGMRCOGABOGFRCSCMRCPI

Red flags

  • Painless cervical dilation with membranes visible at the os in the second trimester — rescue cerclage territory, but only after excluding infection and labour
  • A short cervix in a woman with a prior spontaneous preterm birth before 24 weeks — the best-evidenced responder; do not watch and wait
  • Fever, uterine tenderness or tachycardia with a stitch in situ — chorioamnionitis: the stitch fails and harms in an infected uterus
  • A previously failed vaginal cerclage presenting again — this is the woman to offer transabdominal cerclage next, not another vaginal stitch
  • Cerclage in a multiple pregnancy — not routine; benefit is small or absent and harm is possible
One-line fellowship answer

Cervical cerclage is a suture around the cervix placed for one of three indications — history, ultrasound or examination — to prevent second-trimester loss and spontaneous preterm birth. The responder is the woman with a singleton, a prior spontaneous preterm birth and a cervix under 25 mm before 24 weeks; McDonald and Shirodkar are the vaginal techniques, transabdominal cerclage is reserved for the failed vaginal stitch, and rescue cerclage needs infection and labour excluded first.[1][4][6]

She is 19 weeks pregnant and the speculum shows bulging membranes at the os. She is not in labour and she is not septic — yet. In the next hour you will decide whether a stitch can save this pregnancy, and the answer turns on three things: who benefits, which technique, and what you must exclude before you operate. Cerclage is a narrow-spectrum intervention — powerful in the right phenotype, useless or harmful in the wrong one.[1][10]

Overview and definition

Cervical cerclage places a supportive suture around the cervix to reinforce the internal os and reduce second-trimester loss and spontaneous preterm birth in women judged to have cervical insufficiency.[1][10] The procedure comes in three indication classes and two anatomical approaches, and almost every exam answer hinges on matching the right indication to the right woman.[1]

Three indications: [1][5]

  • History-indicated (prophylactic) — placed electively early in the second trimester on the strength of an obstetric history strongly suggestive of cervical insufficiency, such as recurrent second-trimester losses or prior very preterm births.
  • Ultrasound-indicated — placed when serial transvaginal cervical length screening shows a short cervix, in a woman already at risk.
  • Examination-indicated (rescue/emergency) — placed when the cervix is already dilating painlessly and membranes are visible, after labour and infection are excluded.

Two approaches: [1][7]

  • Transvaginal — McDonald (purse-string at the cervicovaginal junction) and Shirodkar (dissection to place a band higher, nearer the internal os). Removed in the antenatal period, delivery usually vaginal.
  • Transabdominal — open or laparoscopic, the suture placed at the level of the internal os, reserved for the failed vaginal cerclage or the inaccessible cervix. Removed at caesarean.
The responder is a phenotype, not a stitchSay it first and the examiner relaxes: 'Cerclage works in the singleton with a prior spontaneous preterm birth and a short cervix. Outside that phenotype, benefit falls away and harm can follow.'[4][10]
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References12ShowHide
  1. [1]Shennan AH, Story L Cervical Cerclage: Green-top Guideline No. 75 BJOG, 2022.PMID 35199905
  2. [2]MRC/RCOG Working Party on Cervical Cerclage Final report of the Medical Research Council/Royal College of Obstetricians and Gynaecologists multicentre randomised trial of cervical cerclage. MRC/RCOG Working Party on Cervical Cerclage Br J Obstet Gynaecol, 1993.PMID 8334085
  3. [3]To MS, Alfirevic Z, Heath VC, et al. Cervical cerclage for prevention of preterm delivery in women with short cervix: randomised controlled trial Lancet, 2004.PMID 15183621
  4. [4]Berghella V, Rafael TJ, Szychowski JM, et al. Cerclage for short cervix on ultrasonography in women with singleton gestations and previous preterm birth: a meta-analysis Obstet Gynecol, 2011.PMID 21446209
  5. [5]Berghella V, Mackeen AD Cervical length screening with ultrasound-indicated cerclage compared with history-indicated cerclage for prevention of preterm birth: a meta-analysis Obstet Gynecol, 2011.PMID 21691173
  6. [6]Ehsanipoor RM, Seligman NS, Saccone G, et al. Physical Examination-Indicated Cerclage: A Systematic Review and Meta-analysis Obstet Gynecol, 2015.PMID 26241265
  7. [7]Shennan A, Chandiramani M, Bennett P, et al. MAVRIC: a multicenter randomized controlled trial of transabdominal vs transvaginal cervical cerclage Am J Obstet Gynecol, 2020.PMID 31585096
  8. [8]Hodgetts Morton V, Toozs-Hobson P, Moakes CA, et al. Monofilament suture versus braided suture thread to improve pregnancy outcomes after vaginal cervical cerclage (C-STICH): a pragmatic randomised, controlled, phase 3, superiority trial Lancet, 2022.PMID 36273481
  9. [9]Zullo F, Di Mascio D, Chauhan SP, et al. Removal versus retention of cervical cerclage with preterm prelabor rupture of membranes: Systematic review and meta-analysis Eur J Obstet Gynecol Reprod Biol, 2023.PMID 37481990
  10. [10]Alfirevic Z, Stampalija T, Medley N Cervical stitch (cerclage) for preventing preterm birth in singleton pregnancy Cochrane Database Syst Rev, 2017.PMID 28586127
  11. [11]Medley N, Vogel JP, Care A, Alfirevic Z Interventions during pregnancy to prevent preterm birth: an overview of Cochrane systematic reviews Cochrane Database Syst Rev, 2018.PMID 30480756
  12. [12]D'Antonio F, Berghella V, Di Mascio D, et al. Role of progesterone, cerclage and pessary in preventing preterm birth in twin pregnancies: A systematic review and meta-analysis Eur J Obstet Gynecol Reprod Biol, 2021.PMID 33946019

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