O&G · Gynae-surgery — cervical insufficiency and preterm birth prevention
Abdominal and transvaginal cervical cerclage
Also known as Cervical cerclage · Cervical stitch · McDonald suture · Shirodkar suture · Transabdominal cerclage · Rescue cerclage · Cerclage for cervical insufficiency
Exam-exhaustive FRANZCOG fellowship reference on cervical cerclage — history-, ultrasound- and examination-indicated indications; McDonald vs Shirodkar; transabdominal cerclage (open and laparoscopic) for failed vaginal cerclage; rescue cerclage; suture material (C-STICH); PPROM and removal; and the landmark RCTs and meta-analyses (MRC/RCOG, To, Berghella, MAVRIC). RCOG Green-top Guideline No. 75 (2022)-aligned, globally tagged to MRCOG and ABOG.
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Target exams
Red flags
- Painless cervical dilation with membranes visible at the os in the second trimester — rescue cerclage territory, but only after excluding infection and labour
- A short cervix in a woman with a prior spontaneous preterm birth before 24 weeks — the best-evidenced responder; do not watch and wait
- Fever, uterine tenderness or tachycardia with a stitch in situ — chorioamnionitis: the stitch fails and harms in an infected uterus
- A previously failed vaginal cerclage presenting again — this is the woman to offer transabdominal cerclage next, not another vaginal stitch
- Cerclage in a multiple pregnancy — not routine; benefit is small or absent and harm is possible
She is 19 weeks pregnant and the speculum shows bulging membranes at the os. She is not in labour and she is not septic — yet. In the next hour you will decide whether a stitch can save this pregnancy, and the answer turns on three things: who benefits, which technique, and what you must exclude before you operate. Cerclage is a narrow-spectrum intervention — powerful in the right phenotype, useless or harmful in the wrong one.[1][10]
Overview and definition
Cervical cerclage places a supportive suture around the cervix to reinforce the internal os and reduce second-trimester loss and spontaneous preterm birth in women judged to have cervical insufficiency.[1][10] The procedure comes in three indication classes and two anatomical approaches, and almost every exam answer hinges on matching the right indication to the right woman.[1]
- History-indicated (prophylactic) — placed electively early in the second trimester on the strength of an obstetric history strongly suggestive of cervical insufficiency, such as recurrent second-trimester losses or prior very preterm births.
- Ultrasound-indicated — placed when serial transvaginal cervical length screening shows a short cervix, in a woman already at risk.
- Examination-indicated (rescue/emergency) — placed when the cervix is already dilating painlessly and membranes are visible, after labour and infection are excluded.
- Transvaginal — McDonald (purse-string at the cervicovaginal junction) and Shirodkar (dissection to place a band higher, nearer the internal os). Removed in the antenatal period, delivery usually vaginal.
- Transabdominal — open or laparoscopic, the suture placed at the level of the internal os, reserved for the failed vaginal cerclage or the inaccessible cervix. Removed at caesarean.
References12ShowHide
- [1]Shennan AH, Story L Cervical Cerclage: Green-top Guideline No. 75 BJOG, 2022.PMID 35199905
- [2]MRC/RCOG Working Party on Cervical Cerclage Final report of the Medical Research Council/Royal College of Obstetricians and Gynaecologists multicentre randomised trial of cervical cerclage. MRC/RCOG Working Party on Cervical Cerclage Br J Obstet Gynaecol, 1993.PMID 8334085
- [3]To MS, Alfirevic Z, Heath VC, et al. Cervical cerclage for prevention of preterm delivery in women with short cervix: randomised controlled trial Lancet, 2004.PMID 15183621
- [4]Berghella V, Rafael TJ, Szychowski JM, et al. Cerclage for short cervix on ultrasonography in women with singleton gestations and previous preterm birth: a meta-analysis Obstet Gynecol, 2011.PMID 21446209
- [5]Berghella V, Mackeen AD Cervical length screening with ultrasound-indicated cerclage compared with history-indicated cerclage for prevention of preterm birth: a meta-analysis Obstet Gynecol, 2011.PMID 21691173
- [6]Ehsanipoor RM, Seligman NS, Saccone G, et al. Physical Examination-Indicated Cerclage: A Systematic Review and Meta-analysis Obstet Gynecol, 2015.PMID 26241265
- [7]Shennan A, Chandiramani M, Bennett P, et al. MAVRIC: a multicenter randomized controlled trial of transabdominal vs transvaginal cervical cerclage Am J Obstet Gynecol, 2020.PMID 31585096
- [8]Hodgetts Morton V, Toozs-Hobson P, Moakes CA, et al. Monofilament suture versus braided suture thread to improve pregnancy outcomes after vaginal cervical cerclage (C-STICH): a pragmatic randomised, controlled, phase 3, superiority trial Lancet, 2022.PMID 36273481
- [9]Zullo F, Di Mascio D, Chauhan SP, et al. Removal versus retention of cervical cerclage with preterm prelabor rupture of membranes: Systematic review and meta-analysis Eur J Obstet Gynecol Reprod Biol, 2023.PMID 37481990
- [10]Alfirevic Z, Stampalija T, Medley N Cervical stitch (cerclage) for preventing preterm birth in singleton pregnancy Cochrane Database Syst Rev, 2017.PMID 28586127
- [11]Medley N, Vogel JP, Care A, Alfirevic Z Interventions during pregnancy to prevent preterm birth: an overview of Cochrane systematic reviews Cochrane Database Syst Rev, 2018.PMID 30480756
- [12]D'Antonio F, Berghella V, Di Mascio D, et al. Role of progesterone, cerclage and pessary in preventing preterm birth in twin pregnancies: A systematic review and meta-analysis Eur J Obstet Gynecol Reprod Biol, 2021.PMID 33946019