O&G Cases · Early pregnancy care
Wernicke encephalopathy in hyperemesis — emergency management station
Emergency station: clinical Wernicke encephalopathy in hyperemesis gravidarum, with an ED doctor about to give dextrose. Tests recognition of the eye-and-confusion presentation, the thiamine-before-glucose rule, high-dose parenteral thiamine dosing, the multi-system complications, and structured communication with the team. Includes assessor key and marking domains.
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Station brief
Format. Emergency management station, approximately 12 minutes. You are the obstetric registrar called to the ward. The ward nurse and an ED doctor who clerked her are present; your consultant is in theatre and contactable. The assessor will run the clock and feed you new findings. [2]
Candidate instruction. Recognise and manage suspected Wernicke encephalopathy in a hyperemetic woman. Verbalise the time-critical intervention, the drug and dose, the escalation, and your communication with the ED doctor who has prescribed dextrose. [1][2]
References6ShowHide
- [1]Nelson-Piercy C, Dean C, Shehmar M, et al. The Management of Nausea and Vomiting in Pregnancy and Hyperemesis Gravidarum (Green-top Guideline No. 69). BJOG, 2024.PMID 38311315
- [2]Oudman E, Wijnia JW, Oey M, et al. Wernicke's encephalopathy in hyperemesis gravidarum: A systematic review. Eur J Obstet Gynecol Reprod Biol, 2019.PMID 30889425
- [3]da Silva JSV, Seres DS, Sabino K, et al. ASPEN Consensus Recommendations for Refeeding Syndrome. Nutr Clin Pract, 2020.PMID 32115791
- [4]Jansen LAW, Koot MH, Van't Hooft J, et al. The windsor definition for hyperemesis gravidarum: A multistakeholder international consensus definition. Eur J Obstet Gynecol Reprod Biol, 2021.PMID 34555550
- [5]Ebrahimi N, Maltepe C, Bournissen FG, et al. Nausea and vomiting of pregnancy: using the 24-hour Pregnancy-Unique Quantification of Emesis (PUQE-24) scale. J Obstet Gynaecol Can, 2009.PMID 19941704
- [6]Jansen LAW, Shaw V, Grooten IJ, et al. Diagnosis and treatment of hyperemesis gravidarum. CMAJ, 2024.PMID 38621783