O&G Cases · Gynaecological oncology — cancer in pregnancy
Cervical cancer at 19 weeks — multidisciplinary management station
Communication and multidisciplinary-management station on cervical cancer in pregnancy: tests the governing principle and the three decision variables, ALARA imaging with the NIPT/CA-125 pitfalls, the neoadjuvant-chemotherapy-to-bridge-to-fetal-maturity strategy, the trimester rule with the malformation data and contraindicated-agent list, the delivery-timing rule, and honest counselling of the frightened patient. Includes assessor key and marking domains.
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Format. Communication and multidisciplinary-management station, approximately 12 minutes. You are the gynaecology registrar. The consultant, maternal-fetal medicine, medical and radiation oncology, neonatology and psycho-oncology are available via the multidisciplinary team. The assessor will run the clock and probe your management and your communication. [1]
Candidate instruction. Lead the multidisciplinary management of cervical cancer diagnosed at 19 weeks in a woman wishing to continue the pregnancy. State the governing principle, justify your staging, defend the treatment plan that allows continuation, apply the rules of chemotherapy in pregnancy, and counsel the patient. Verbalise your reasoning and your communication. [1]
References6ShowHide
- [1]Amant F, Planchamp F, Berveiller P, et al. ESGO/INCIP Guidelines for the management of patients with gynecological cancers during pregnancy Int J Gynecol Cancer, 2025.PMID 40707270
- [2]Loren AW, Lacchetti C, Amant F, et al. Management of Cancer During Pregnancy: ASCO Guideline J Clin Oncol, 2026.PMID 41380115
- [3]van Gerwen M, Maggen C, Cardonick E, et al. Association of Chemotherapy Timing in Pregnancy With Congenital Malformation JAMA Netw Open, 2021.PMID 34106263
- [4]Karam A, Feldman N, Holschneider CH Neoadjuvant cisplatin and radical cesarean hysterectomy for cervical cancer in pregnancy Nat Clin Pract Oncol, 2007.PMID 17534393
- [5]Amant F, Van Calsteren K, Halaska MJ, et al. Long-term cognitive and cardiac outcomes after prenatal exposure to chemotherapy in children aged 18 months or older: an observational study Lancet Oncol, 2012.PMID 22326925
- [6]Wolters V, Heimovaara J, Maggen C, et al. Management of pregnancy in women with cancer Int J Gynecol Cancer, 2021.PMID 33649001