ICU SAQs · Haematology / transfusion
TRALI vs TACO — the pulmonary reaction after the transfusion
A CICM SAQ on the TRALI vs TACO — the TACO (the overload, the hypertension, the positive balance — the diuretics) vs the TRALI (the euvolaemic, the ARDS-like, the NO diuretics — the supportive), and the reporting.
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Prompt
A 65-year-old with the heart failure develops the hypoxia and the bilateral infiltrates 2 hours after a 2-unit RBC transfusion. The BP 160/90, the fluid balance +3L. Is this TRALI or TACO, and what is the management?
Question
A 65-year-old with the heart failure develops the hypoxia and the bilateral infiltrates 2 hours after a 2-unit RBC transfusion. The BP 160/90, the fluid balance +3L. Is this TRALI or TACO, and what is the management?[1][2]
References3ShowHide
- [1]Vlaar AP, Juffermans NP Transfusion-related acute lung injury: a clinical review Lancet, 2013.PMID 23642914
- [2]Semple JW, Rebetz J, Kapur R, et al. Transfusion-associated circulatory overload and transfusion-related acute lung injury Blood, 2019.PMID 30808638
- [3]Klanderman RB, Bosboom JJ, Migdady Y, et al. Transfusion-associated circulatory overload-a systematic review of diagnostic biomarkers Transfusion, 2019.PMID 30488959