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ICU SAQsToxicology

ICU SAQs · Toxicology

The GHB overdose — the management

A CICM Second-Part SAQ on the GHB overdose — the rapid-resolving coma, the airway/aspiration, the no-antidote supportive care.

10 marks10 min1 min readSource-verified ·

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CICMFFICMEDIC
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Target exams

CICMFFICMEDIC
Prompt
A 20-year-old is brought to the ED deeply comatose 30 minutes after suspected recreational drug use at a nightclub, with bradycardia and vomiting. Outline the management.

Question

A 20-year-old is brought to the ED deeply comatose 30 minutes after suspected recreational drug use at a nightclub, with bradycardia and vomiting. Outline the management.

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References3ShowHide
  1. [1]Schep LJ, Knudsen K, Slaughter RJ, et al. The clinical toxicology of gamma-hydroxybutyrate, gamma-butyrolactone and 1,4-butanediol. Clinical Toxicology (Philadelphia), 2012.PMID 22746383
  2. [4]Bersten AD, Soni N (eds) Oh's Intensive Care Manual. 8th edition, Elsevier, 2018.
  3. [5]Dahan A, Franko TS, Carroll JW, et al. Fact vs. fiction: naloxone in the treatment of opioid-induced respiratory depression in the current era of synthetic opioids Front Public Health, 2024.PMID 38481848
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