ICU SAQs · Toxicology
Superwarfarin (brodifacoum) poisoning — the management
A CICM Second-Part SAQ on the superwarfarin poisoning — the PCC + vitamin K, the prolonged (the months) vitamin K course.
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Prompt
A patient presents with gross haematuria and epistaxis, INR above the measurable range, on no anticoagulants, with a history of pest-control work. Outline the management.
Question
A patient presents with gross haematuria and epistaxis, INR above the measurable range, on no anticoagulants, with a history of pest-control work. Outline the management.
[4]References4ShowHide
- [1]King N, Tran MH Long-Acting Anticoagulant Rodenticide (Superwarfarin) Poisoning: A Review. Transfusion Medicine Reviews, 2015.PMID 26239439
- [2]Ostermann H, von Heymann C Prothrombin complex concentrate for vitamin K antagonist reversal in acute major bleeding. Expert Review of Hematology, 2019.PMID 31159607
- [3]Bersten AD, Soni N (eds) Oh's Intensive Care Manual. 8th edition, Elsevier, 2018.
- [4]Douxfils J, Ageno W, Samama CM, et al. Laboratory testing in patients treated with direct oral anticoagulants: a practical guide for clinicians J Thromb Haemost, 2018.PMID 29193737