ICU SAQs · Statistics & evidence
Critical appraisal of an ICU trial — the SOAP II worked example
A CICM Second-Part SAQ on critical appraisal — the SOAP II trial (norepinephrine vs dopamine), the design, the validity, the result, the importance, the applicability, and the practice change.
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Prompt
Critically appraise the SOAP II trial (De Backer, NEJM 2010) of the dopamine vs the norepinephrine in the shock.
Question
Critically appraise the SOAP II trial (De Backer, NEJM 2010) of the dopamine vs the norepinephrine in the shock.
[2]References2ShowHide
- [2]De Backer D, Biston P, Devriendt J, et al. Comparison of dopamine and norepinephrine in the treatment of shock (SOAP II). New England Journal of Medicine, 2010.PMID 20200382
- [9]Bersten AD, Soni N (eds) Oh's Intensive Care Manual. 8th edition, Elsevier, 2018.