ICU SAQs · Resuscitation
The determinants of oxygen delivery
A CICM First-Part basic-science SAQ on oxygen delivery — DO2 = CO × CaO2; the cardiac output (HR × SV, and its determinants) and the arterial oxygen content (Hb × saturation × 1.34 + dissolved O2); and how failure of each produces the four shock types and directs the resuscitation.
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Prompt
Derive global oxygen delivery from first principles. Identify each determinant and explain how failure of each produces shock, and how resuscitation targets the failed determinant.
Question
Derive global oxygen delivery from first principles. Identify each determinant and explain how failure of each produces shock, and how resuscitation targets the failed determinant.[1]
References3ShowHide
- [1]Bersten AD, Soni N (eds) Oh's Intensive Care Manual. 8th edition, Elsevier, 2018.
- [2]Marino PL The ICU Book. 4th edition, Lippincott Williams & Wilkins, 2014.
- [3]Rivers E, Nguyen B, Havstad S, et al. Early goal-directed therapy in the treatment of severe sepsis and septic shock. New England Journal of Medicine, 2001.PMID 11794169