ICU SAQs · Infection / pharmacology
Vancomycin for the MRSA — dosing, the red-man, and the VANCO-ZOSYN AKI
A CICM SAQ on the vancomycin — the AUC-over-MIC-guided dosing (the 400 to 600), the weight-based loading, the red-man syndrome (the histamine, not the allergy), and the VANCO-ZOSYN AKI (the cefepime alternative).
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Prompt
A 90-kg patient with the MRSA bacteraemia is started on the vancomycin plus the piperacillin-tazobactam. Discuss the vancomycin dosing and monitoring, and the renal considerations.
Question
A 90-kg patient with the MRSA bacteraemia is started on the vancomycin plus the piperacillin-tazobactam. Discuss the vancomycin dosing and monitoring, and the renal considerations.[1]
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- [1]Bersten AD, Soni N (eds) Oh's Intensive Care Manual. 8th edition, Elsevier, 2018.