ICU SAQs · Endocrine & metabolic emergencies
SIADH — the management
A CICM Second-Part SAQ on the SIADH with severe symptomatic hyponatraemia — the hypertonic saline (the cautious, the osmotic demyelination), the correction rate.
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Prompt
A 60-year-old with small-cell lung cancer presents with confusion and seizures, Na 112 mmol/L, plasma osmolality 250, urine osmolality 400, urine Na 60. Outline the management.
Question
A 60-year-old with small-cell lung cancer presents with confusion and seizures, Na 112 mmol/L, plasma osmolality 250, urine osmolality 400, urine Na 60. Outline the management.[1]
References2ShowHide
- [1]Warren AM, Grossmann M, Christ-Crain M, et al. Syndrome of Inappropriate Antidiuresis: From Pathophysiology to Management. Endocrine Reviews, 2023.PMID 36974717
- [4]Verbalis JG, Grossman A, Höybye C, et al. Review and analysis of differing regulatory indications and expert panel guidelines for the treatment of hyponatremia Curr Med Res Opin, 2014.PMID 24809970