ICU SAQs · Endocrine & metabolic emergencies
The sulfonylurea-induced hypoglycaemia — the management
A CICM Second-Part SAQ on the sulfonylurea hypoglycaemia — the octreotide (the not the dextrose alone), the prolonged the monitoring.
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Prompt
An elderly diabetic on glibenclamide presents unconscious with a glucose of 1.5 mmol/L, recovering briefly with IV dextrose but recurring. Outline the management.
Question
An elderly diabetic on glibenclamide presents unconscious with a glucose of 1.5 mmol/L, recovering briefly with IV dextrose but recurring. Outline the management.[2]
References4ShowHide
- [2]Lheureux PE, Zahir S, Penaloza A, et al. Bench-to-bedside review: Antidotal treatment of sulfonylurea-induced hypoglycemia. Critical Care, 2005.PMID 16356235
- [3]Glatstein M, Scolnik D, Bentur Y Octreotide for the treatment of sulfonylurea poisoning. Clinical Toxicology (Philadelphia), 2012.PMID 23046209
- [4]Finfer S, Liu B, Chittock DR, et al. Hypoglycemia and risk of death in critically ill patients. N Engl J Med, 2012.PMID 22992074
- [5]Hurtubise M, Stirling J, Greene J, et al. Dextrose 50% versus Dextrose 10% or Dextrose Titration for the Treatment of Out-of-Hospital Hypoglycemia: A Systematic Review Prehosp Disaster Med, 2021.PMID 34605385