ICU Cases · Statistics & evidence
Calculating the NNT from a trial
A short case calculating the effect sizes — the RR, the ARR, the RRR, the NNT — from the ARMA low-tidal-volume trial data.
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Prompt
A short case calculating the effect sizes — the RR, the ARR, the RRR, the NNT — from the ARMA low-tidal-volume trial data.
Presentation
The ARMA trial reported the mortality of 40 per cent with the traditional (12 mL/kg) tidal volume and 31 per cent with the low (6 mL/kg) tidal volume in the ARDS. Calculate the RR, the ARR, the RRR and the NNT.
[1]References2ShowHide
- [1]Brower RG, Matthay MA, Morris A, et al. Ventilation with lower tidal volumes as compared with traditional tidal volumes for acute lung injury and the acute respiratory distress syndrome. New England Journal of Medicine, 2000.PMID 10793162
- [9]Bersten AD, Soni N (eds) Oh's Intensive Care Manual. 8th edition, Elsevier, 2018.