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ICU CasesResuscitation

ICU Cases · Resuscitation

Hot case — vasopressor-dependent septic shock on day 2

A CICM Second-Part hot case — the College's hallmark real-patient bedside encounter. The candidate synthesises a deteriorating day-2 septic shock patient, examines at the bedside, presents a focused assessment, defends a management plan, and answers the examiner's probes.

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Prompt
You are handed a 59-year-old woman in bay 4. She was admitted 30 hours ago with septic shock from a biliary source, is now intubated, and is on rising doses of noradrenaline. You have eight minutes to review the chart and examine her before the examiner joins you at the bedside.

Presentation

Candidate brief. Mrs K, 59, admitted 30 hours ago with rigors and right-upper-quadrant pain, diagnosed with ascending cholangitis and septic shock. She was intubated for work of breathing and a falling Glasgow Coma Scale, had an endoscopic retrograde cholangiopancreatography (ERCP) with stone extraction and stent insertion 18 hours ago, and is now in the unit on noradrenaline at 0.4 mcg/kg/min, MAP 62 mmHg, lactate 3.6 mmol/L (down from 7.1), oliguric, and febrile at 38.6 °C. The bedside nurse reports the noradrenaline has crept up over the last three hours.

[1]

You have eight minutes to review the chart, examine the patient, and prepare a structured presentation before the examiner arrives.[6]

ICU Fellowship (CICM) Pro

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You have read the opening of this case. The complete unit — every section and its primary-source references — is part of the ICU Fellowship (CICM) fellowship library.

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References6ShowHide
  1. [1]Evans L, Rhodes A, Alhazzani W, et al. Surviving Sepsis Campaign: International Guidelines for Management of Sepsis and Septic Shock 2021. Intensive Care Medicine, 2021.PMID 34599691
  2. [2]Asfar P, Meziani F, Hamel JF, et al. High versus Low Blood-Pressure Target in Patients with Septic Shock (SEPSISPAM). New England Journal of Medicine, 2014.PMID 24635770
  3. [3]Rowan KM, Angus DC, Bailey M, et al. Early, Goal-Directed Therapy for Septic Shock — A Patient-Level Meta-Analysis. New England Journal of Medicine, 2017.PMID 28320242
  4. [4]Venkatesh B, Finfer S, Cohen J, et al. Adjunctive Glucocorticoid Therapy in Patients with Septic Shock. New England Journal of Medicine, 2018.PMID 29347874
  5. [5]Annane D, Renault A, Brun-Buisson C, et al. Hydrocortisone plus Fludrocortisone for Adults with Septic Shock (APROCCHSS). New England Journal of Medicine, 2018.PMID 29490185
  6. [6]Seymour CW, Gesten F, Prescott HC, et al. Time to Treatment and Mortality during Mandated Emergency Care for Sepsis. New England Journal of Medicine, 2017.PMID 28528569
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