ICU Cases · Resuscitation
Hot case — vasopressor-dependent septic shock on day 2
A CICM Second-Part hot case — the College's hallmark real-patient bedside encounter. The candidate synthesises a deteriorating day-2 septic shock patient, examines at the bedside, presents a focused assessment, defends a management plan, and answers the examiner's probes.
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Candidate brief. Mrs K, 59, admitted 30 hours ago with rigors and right-upper-quadrant pain, diagnosed with ascending cholangitis and septic shock. She was intubated for work of breathing and a falling Glasgow Coma Scale, had an endoscopic retrograde cholangiopancreatography (ERCP) with stone extraction and stent insertion 18 hours ago, and is now in the unit on noradrenaline at 0.4 mcg/kg/min, MAP 62 mmHg, lactate 3.6 mmol/L (down from 7.1), oliguric, and febrile at 38.6 °C. The bedside nurse reports the noradrenaline has crept up over the last three hours.
[1]You have eight minutes to review the chart, examine the patient, and prepare a structured presentation before the examiner arrives.[6]
References6ShowHide
- [1]Evans L, Rhodes A, Alhazzani W, et al. Surviving Sepsis Campaign: International Guidelines for Management of Sepsis and Septic Shock 2021. Intensive Care Medicine, 2021.PMID 34599691
- [2]Asfar P, Meziani F, Hamel JF, et al. High versus Low Blood-Pressure Target in Patients with Septic Shock (SEPSISPAM). New England Journal of Medicine, 2014.PMID 24635770
- [3]Rowan KM, Angus DC, Bailey M, et al. Early, Goal-Directed Therapy for Septic Shock — A Patient-Level Meta-Analysis. New England Journal of Medicine, 2017.PMID 28320242
- [4]Venkatesh B, Finfer S, Cohen J, et al. Adjunctive Glucocorticoid Therapy in Patients with Septic Shock. New England Journal of Medicine, 2018.PMID 29347874
- [5]Annane D, Renault A, Brun-Buisson C, et al. Hydrocortisone plus Fludrocortisone for Adults with Septic Shock (APROCCHSS). New England Journal of Medicine, 2018.PMID 29490185
- [6]Seymour CW, Gesten F, Prescott HC, et al. Time to Treatment and Mortality during Mandated Emergency Care for Sepsis. New England Journal of Medicine, 2017.PMID 28528569